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. 1978 Jan;19(1):56–59. doi: 10.1136/gut.19.1.56

Relationship between splenic size and splenic function.

R C Smart, F P Ryan, C D Holdworth, F E Preston
PMCID: PMC1411781  PMID: 624507

Abstract

The rate of clearance of 51Cr labelled heat-damaged red cells from the circulation has been compared with the dimensions of the posterior scan of the spleen in 79 cases including nine controls. A strong negative correlation was found between the clearance half-time and the parameters of the scan but, as there was a large variation about the regression line, in the assessment of hyposplenism determination of the rate of clearance of heat-damaged red cells cannot be replaced by the easier determination of spleen size by scanning.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker P. G., Jones J. V., Peacock D. B., Read A. E. The immune response of phiX 174 in man. III. Evidence for an association between hyposplenism and immunodeficiency in patients with coeliac disease. Gut. 1975 Jul;16(7):538–542. doi: 10.1136/gut.16.7.538. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. HOLZBACH R. T., SHIPLEY R. A., CLARK R. E., CHUDZIK E. B. INFLUENCE OF SPLEEN SIZE AND PORTAL PRESSURE ON ERYTHROCYTE SEQUESTRATION. J Clin Invest. 1964 Jun;43:1125–1135. doi: 10.1172/JCI104997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Keeling D. H., Newman G. B., Baker J. T., Millett Y. Estimation of splenic volume in vivo. Br J Radiol. 1971 May;44(521):403–403. [PubMed] [Google Scholar]
  4. Marsh G. W., Lewis S. M., Szur L. The use of 51Cr-labelled heat-damaged red cells to study splenic function. I. Evaluation of method. Br J Haematol. 1966 Mar;12(2):161–166. doi: 10.1111/j.1365-2141.1966.tb05620.x. [DOI] [PubMed] [Google Scholar]
  5. Marsh G. W., Stewart J. S. Splenic function in adult coeliac disease. Br J Haematol. 1970 Oct;19(4):445–457. doi: 10.1111/j.1365-2141.1970.tb06972.x. [DOI] [PubMed] [Google Scholar]
  6. Pearson H. A., Spencer R. P., Cornelius E. A. Functional asplenia in sickle-cell anemia. N Engl J Med. 1969 Oct 23;281(17):923–926. doi: 10.1056/NEJM196910232811703. [DOI] [PubMed] [Google Scholar]
  7. Pettit J. E., Williams E. D., Glass H. I., Lewis S. M., Szur L., Wicks C. J. Studies of splenic function in the myeloproliferative disorders and generalized malignant lymphomas. Br J Haematol. 1971 Jun;20(6):575–586. doi: 10.1111/j.1365-2141.1971.tb00796.x. [DOI] [PubMed] [Google Scholar]
  8. Ryan F. P., Smart R., Preston F. E., Holdsworth C. D. Hyposplenism in ulcerative colitis. Lancet. 1974 Aug 10;2(7876):318–320. doi: 10.1016/s0140-6736(74)91695-x. [DOI] [PubMed] [Google Scholar]
  9. Spencer R. P. Estimation of functional size of the spleen. J Nucl Med. 1970 Oct;11(10):616–616. [PubMed] [Google Scholar]

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