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. 1978 Apr;19(4):273–276. doi: 10.1136/gut.19.4.273

Absence of K cells in human gut mucosa.

R Clancy, A Pucci
PMCID: PMC1411922  PMID: 648935

Abstract

Lymphocytes have been isolated from human rectal biopsies in numbers sufficient for microassay procedures. No antibody-dependent cell-mediated cytotoxic (ADCC) activity could be detected in normal or inflamed human gut mucosa, using two assay systems which detect predominantly K cell activity. The tissue localisation and circulation characteristics of K cells require definition before establishing their role as an efferent immunological mechanism.

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Selected References

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