Abstract
The uniformity of mucosal morphology within the distal duodenum and the first loop of jejunum, ie, the area usually biopsied, was examined at necropsy in 116 children. In those with no evidence of gastrointestinal disease there was no significant variation within this area, but in 25 children with mucosal abnormality, variation occurred within a small area. The crests of the plicae circulares were more often more severely abnormal than the area in the valleys between. Owing to the small size of biopsy specimens, it is apparent from this study that such specimens may not be representative of the proximal small intestinal mucosa in children suffering from the disorders of the small intestine encountered in this study.
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- Creamer B., Leppard P. Post-mortem examination of a small intestine in the coeliac syndrome. Gut. 1965 Oct;6(5):466–471. doi: 10.1136/gut.6.5.466. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Symposium on disease of the small intestine in children. Med J Aust. 1971 Apr 10;1(15):816–824. doi: 10.5694/j.1326-5377.1971.tb87877.x. [DOI] [PubMed] [Google Scholar]
- Walker-Smith J. A., Reye R. D., Soutter G. B., Kenrick K. G. Small intestinal lymphangioma. Arch Dis Child. 1969 Aug;44(236):527–532. doi: 10.1136/adc.44.236.527. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Walker-Smith J. A. Small bowel morphology in childhood. Med J Aust. 1969 Feb 22;1(8):382–387. doi: 10.5694/j.1326-5377.1969.tb92167.x. [DOI] [PubMed] [Google Scholar]
- Weinstein W. M., Brow J. R., Parker F., Rubin C. E. The small intestinal mucosa in dermatitis herpetiformis. II. Relationship of the small intestinal lesion to gluten. Gastroenterology. 1971 Mar;60(3):362–369. [PubMed] [Google Scholar]