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. 1979 Aug;20(8):730–734. doi: 10.1136/gut.20.8.730

Double-blind controlled trial of cimetidine in the healing of gastric ulcer.

P J Ciclitira, R J Machell, J G Farthing, A P Dick, J O Hunter
PMCID: PMC1412542  PMID: 385458

Abstract

Sixty patients with gastric ulcers were treated for four weeks with either 1 g cimetidine per day or with identical tablets containing lactose. The healing rate, assessed by endoscopy, was 23 out of 35 (66%) in the patients given cimetidine and 13 out of 25 (52%) in those given placebo. The difference between the groups is not significant. During each of the four weeks of the study the cimetidine group experienced significantly fewer attacks of pain and consumed less antacids than the placebo treated patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dyck W. P., Belsito A., Fleshler B., Liebermann T. R., Dickinson P. B., Wood J. M. Cimetidine and placebo in the treatment of benign gastric ulcer: a multicenter double blind study. Gastroenterology. 1978 Feb;74(2 Pt 2):410–415. [PubMed] [Google Scholar]
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