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. 1973 Jan;14(1):20–24. doi: 10.1136/gut.14.1.20

Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease

P J Guillou, T G Brennan, G R Giles
PMCID: PMC1412585  PMID: 4692250

Abstract

The response of lymphocytes from peripheral blood and mesenteric lymph nodes to stimulation with phytohaemagglutinin in vitro has been studied in eight patients suffering from active Crohn's disease. Patients with Crohn's disease exhibited reduced responses when compared with similar studies performed in control subjects. The impaired responses of circulating lymphocytes from these patients were marked on culture in autologous serum and were not improved by culture in homologous AB serum. Lymphocytes from lymph nodes directly draining diseased bowel exhibited lower responses than those from nodes at the root of the mesentery, which in turn were lower than those of circulating lymphocytes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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