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. 1979 Dec;20(12):1057–1062. doi: 10.1136/gut.20.12.1057

Virus isolation studies in Crohn's disease: a negative report.

R J Phillpotts, J Hermon-Taylor, B N Brooke
PMCID: PMC1412821  PMID: 527878

Abstract

Homogenates of gut and mesenteric lymph node tissue from patients with Crohn's disease, ulcerative colitis, and control patients were tested for cytopathic effect (CPE) production in a series of cell lines including rabbit ileal and W138 cells. A CPE was produced in W138 cells by tissue homogenates from patients with Crohn's disease, ulcerative colitis, and control patients. Evidence was obtained to suggest that this effect, although superficially similar to a viral CPE, was due to toxic protein constituents of inflamed tissue homogenate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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