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. 1974 Aug;15(8):626–629. doi: 10.1136/gut.15.8.626

A duodenal role in gastrin release

J R Hayes, Joy Ardill, T L Kennedy, K D Buchanan
PMCID: PMC1413028  PMID: 4422726

Abstract

Observations on the plasma gastrin response to feeding protein in patients with the dumping syndrome, patients with pyloric stenosis, and patients asymptomatic after gastric surgery suggested that the duodenum might be important in the mechanism of gastrin release. This duodenal role was confirmed by the finding that when the stimulus was placed directly in the duodenum peak gastrin levels occurred earlier than when the stimulus was placed directly in the stomach.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berson S. A., Yllow R. S. Nature of immunoreactive gastrin extracted from tissues of gastrointestinal tract. Gastroenterology. 1971 Feb;60(2):215–222. [PubMed] [Google Scholar]
  2. Korman M. G., Soveny C., Hansky J. Serum gastrin in duodenal ulcer. I. Basal levels and effect of food and atropine. Gut. 1971 Nov;12(11):899–902. doi: 10.1136/gut.12.11.899. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. McGuigan J. E., Trudeau W. L. Serum gastrin levels before and after vagotomy and pyloroplasty or vagotomy and antrectomy. N Engl J Med. 1972 Jan 27;286(4):184–188. doi: 10.1056/NEJM197201272860404. [DOI] [PubMed] [Google Scholar]
  4. RETZER O., MORRISON M., HARRISON R. C. The effect of gastroenterostomy on gastric secretion. Surg Gynecol Obstet. 1960 Sep;111:285–288. [PubMed] [Google Scholar]
  5. WOODWARD E. R., LYON E. S., LANDOR J., DRAGSTEDT L. R. The physiology of the gastric antrum; experimental studies on isolated antrum pouches in dogs. Gastroenterology. 1954 Dec;27(6):766–785. [PubMed] [Google Scholar]
  6. Walsh J. H., Yalow R. S., Berson S. A. The effect of atropine on plasma gastrin response to feeding. Gastroenterology. 1971 Jan;60(1):16–21. [PubMed] [Google Scholar]

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