Abstract
Porcine calcitonin given to guinea pigs in doses causing hypocalcaemia and hypophosphataemia decreased the bilirubin concentration and increased the activity of gamma glutamyl transpeptidase (GGTP) in the hepatic bile. Calcitonin had no effect on bile flow, its pH, electrolyte composition including calcium, or on the concentration of protein, glucose, cholesterol, nonprotein nitrogen (NPN), and bile acids. It also did not affect the activities of alanine aminotransferase (AIAT) and alkaline phosphatase (AP) in the hepatic bile. Calcitonin increased the calcium content in the liver.
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Selected References
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- Case R. M. Calcium and gastrointestinal secretion. Digestion. 1973;8(3):269–288. doi: 10.1159/000197324. [DOI] [PubMed] [Google Scholar]
- Hesch R. D., Hüfner M., Hasenhager B., Creutzfeldt W. Inhibition of gastric secretion by calcitonin in man. Horm Metab Res. 1971 Mar;3(2):140–140. doi: 10.1055/s-0028-1096771. [DOI] [PubMed] [Google Scholar]
- Hirsch P. F., Munson P. L. Thyrocalcitonin. Physiol Rev. 1969 Jul;49(3):548–622. doi: 10.1152/physrev.1969.49.3.548. [DOI] [PubMed] [Google Scholar]
- Hotz J., Widmaier F., Minne H., Ziegler R. Serum calcium and gastric secretion in chronic gastric fistula rat: influences of parathyroid hormone and calcitonin. Eur J Clin Invest. 1971 Sep;1(6):486–490. doi: 10.1111/j.1365-2362.1971.tb00560.x. [DOI] [PubMed] [Google Scholar]
- Kirchmayer S., Tarnawski A., Drozdz H., Cichecka K. Effect of cholecystokinin-pancreozymin and secretin on the volume, composition, and enzymatic activity of hepatic bile in rabbits. Gut. 1972 Sep;13(9):709–712. doi: 10.1136/gut.13.9.709. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pak C. Y. Parathyroid hormone and thyrocalcitonin: their mode of action and regulation. Ann N Y Acad Sci. 1971 Jul 6;179:450–474. doi: 10.1111/j.1749-6632.1971.tb46922.x. [DOI] [PubMed] [Google Scholar]
- Talmage R. V., Anderson J. J. The effect of calcitonin on 32 P disappearance from plasma in parathyroidectomized and nephrectomized rats. Proc Soc Exp Biol Med. 1972 Dec;141(3):982–985. doi: 10.3181/00379727-141-36915. [DOI] [PubMed] [Google Scholar]