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. 1974 Nov;15(11):903–906. doi: 10.1136/gut.15.11.903

Thoracic duct and hepatic lymph in idiopathic portal hypertension

A K S Samanta, V K Saini, P N Chhuttani, B S Patra, S Vashista, D V Datta
PMCID: PMC1413063  PMID: 4455569

Abstract

Lymph dynamics in idiopathic portal hypertension has been studied in two phases. In the first phase thoracic duct lymph transport was studied in 11 patients with idiopathic portal hypertension by cannulating the duct. This revealed altered lymph transport in the form of a distended thoracic duct, raised pressure in the duct, and haemorrhagic lymph with an increased flow rate. The lymph flow rate was analysed in relation to various hepatic haemodynamic and biochemical parameters. In the second phase of the study hepatic lymphatics were studied by percutaneous hepatography in 16 patients with idiopathic portal hypertension. By this technique hepatic lymphatics were opacified in patients with idiopathic portal hypertension and cirrhosis with equal frequency. The significance of this finding in relation to the altered hepatic haemodynamics and thoracic duct lymph transport is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AIELLO R. G., ENQUIST I. F., IKEZONO E., LEVOWITZ B. S. An experimental study of the role of hepatic lymph in the production of ascites. Surg Gynecol Obstet. 1960 Jul;111:77–81. [PubMed] [Google Scholar]
  2. BAGGENSTOSS A. H., CAIN J. The hepatic hilar lymphatics of man; their relation to ascites. N Engl J Med. 1957 Mar 21;256(12):531–535. doi: 10.1056/NEJM195703212561201. [DOI] [PubMed] [Google Scholar]
  3. BOWERS W. F., MCKINNON W. M., MARINO J. M., CULVERWELL J. T. CANNULATION OF THE THORACIC DUCT: ITS ROLE IN THE PRE-SHUNT MANAGEMENT OF HEMORRHAGE DUE TO ESOPHAGEAL VARICES. J Int Coll Surg. 1964 Jul;42:71–76. [PubMed] [Google Scholar]
  4. Basu A. K., Boyer J., Bhattacharya R., Mallik K. C., Sen Gupta K. P. Non-cirrhotic portal fibrosis with portal hypertension: a new syndrome. I. Clinical and function studies and results of operations. Indian J Med Res. 1967 Apr;55(4):336–350. [PubMed] [Google Scholar]
  5. CAESAR J., SHALDON S., CHIANDUSSI L., GUEVARA L., SHERLOCK S. The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function. Clin Sci. 1961 Aug;21:43–57. [PubMed] [Google Scholar]
  6. Clain D., McNulty J. A radiological study of the lymphatics of the liver. Br J Radiol. 1968 Sep;41(489):662–668. doi: 10.1259/0007-1285-41-489-662. [DOI] [PubMed] [Google Scholar]
  7. DUMONT A. E., MULHOLLAND J. H. Flow rate and composition of thoracic-duct lymph in patients with cirrhosis. N Engl J Med. 1960 Sep 8;263:471–474. doi: 10.1056/NEJM196009082631001. [DOI] [PubMed] [Google Scholar]
  8. Datta D. V., Singh S. A., Patra B. S., Saini V. K., Chhuttani P. N. Management of bleeding oesophageal varices by draining lymph from the thoracic duct. Gut. 1971 Jan;12(1):48–50. doi: 10.1136/gut.12.1.48. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kessler R. E., Santoni E., Tice D. A., Zimmon D. S. Effect of lymph drainage on portal pressure and bleeding esophageal varices. Gastroenterology. 1969 Mar;56(3):538–547. [PubMed] [Google Scholar]
  10. Mallik K. C., Sen Gupta K. P., Basu A. K., Biswas S. K., Pal N. C., Boyer J. Non-cirrhotic portal fibrosis with portal hypertension: a new syndrome. II. Histopathological studies. Indian J Med Res. 1967 Apr;55(4):351–359. [PubMed] [Google Scholar]
  11. Witte M. H., Dumont A. E., Cole W. R., Witte C. L., Kintner K. Lymph circulation in hepatic cirrhosis: effect of portacaval shunt. Ann Intern Med. 1969 Feb;70(2):303–310. doi: 10.7326/0003-4819-70-2-303. [DOI] [PubMed] [Google Scholar]
  12. ZEPPA R., WOMACK N. A. Humoral control of hepatic lymph flow. Surgery. 1963 Jul;54:37–44. [PubMed] [Google Scholar]

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