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. 1985 Mar 9;290(6470):744–745. doi: 10.1136/bmj.290.6470.744

Hepatic sequestration in sickle cell anaemia.

C S Hatton, C Bunch, D J Weatherall
PMCID: PMC1418512  PMID: 3918737

Abstract

Several episodes of acute hepatic enlargement associated with a dramatic fall in haemoglobin concentration were observed in two patients with sickle cell anaemia. No appreciable disturbances of liver function or signs of cardiac failure were evident. The most likely mechanism was sequestration of sickled erythrocytes in the liver. This complication, which may have a basis similar to that of splenic sequestration and the sickle lung syndrome, may be easily overlooked unless the size of the liver is regularly monitored in patients with sickle cell crisis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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