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. 1985 Apr 20;290(6476):1171–1173. doi: 10.1136/bmj.290.6476.1171

Effect of aspirin on nasal resistance to airflow.

A S Jones, J M Lancer, A A Moir, J C Stevens
PMCID: PMC1418864  PMID: 3921141

Abstract

The effect of aspirin on nasal resistance to airflow was investigated by rhinomanometry in 25 healthy subjects before and after ingestion of aspirin or vitamin C in a double blind crossover trial. Aspirin caused a significant increase in nasal resistance compared with vitamin C. The effect of aspirin may be due to its inhibition of the synthesis of prostaglandins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anggard A. The effect of prostaglandins on nasal airway resistance in man. Ann Otol Rhinol Laryngol. 1969 Jun;78(3):657–662. doi: 10.1177/000348946907800320. [DOI] [PubMed] [Google Scholar]
  2. Asad S. I., Kemeny D. M., Youlten L. J., Frankland A. W., Lessof M. H. Effect of aspirin in "aspirin sensitive" patients. Br Med J (Clin Res Ed) 1984 Mar 10;288(6419):745–748. doi: 10.1136/bmj.288.6419.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Asad S. I., Youlten L. J., Lessof M. H. Specific desensitization in 'aspirin-sensitive' urticaria; plasma prostaglandin levels and clinical manifestations. Clin Allergy. 1983 Sep;13(5):459–466. doi: 10.1111/j.1365-2222.1983.tb02622.x. [DOI] [PubMed] [Google Scholar]
  4. Bedwani J. R., Eccles R., Jones A. S. Effects of prostaglandins E2, I2 and D2 on pig nasal vasculature. Clin Otolaryngol Allied Sci. 1983 Oct;8(5):337–341. [PubMed] [Google Scholar]
  5. Bedwani J. R., Eccles R., Jones A. S. The isolation of prostaglandin E from pig nasal mucosa. Clin Otolaryngol Allied Sci. 1983 Jun;8(3):159–163. doi: 10.1111/j.1365-2273.1983.tb01420.x. [DOI] [PubMed] [Google Scholar]
  6. Clement P. A. Committee report on standardization of rhinomanometry. Rhinology. 1984 Sep;22(3):151–155. [PubMed] [Google Scholar]
  7. Dallimore N. S., Eccles R. Changes in human nasal resistance associated with exercise, hyperventilation and rebreathing. Acta Otolaryngol. 1977 Nov-Dec;84(5-6):416–421. doi: 10.3109/00016487709123985. [DOI] [PubMed] [Google Scholar]
  8. Eccles R., Jones A. S. The effect of menthol on nasal resistance to air flow. J Laryngol Otol. 1983 Aug;97(8):705–709. doi: 10.1017/s002221510009486x. [DOI] [PubMed] [Google Scholar]
  9. Eccles R. The central rhythm of the nasal cycle. Acta Otolaryngol. 1978 Nov-Dec;86(5-6):464–468. doi: 10.3109/00016487809107526. [DOI] [PubMed] [Google Scholar]
  10. STOKSTED P. Rhinometric measurements for determination of the nasal cycle. Acta Otolaryngol Suppl. 1953;109:159–175. doi: 10.3109/00016485309132516. [DOI] [PubMed] [Google Scholar]
  11. Solow B., Greve E. Rhinomanometric recording in children. Rhinology. 1980 Mar;18(1):31–42. [PubMed] [Google Scholar]
  12. Vane J. R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232–235. doi: 10.1038/newbio231232a0. [DOI] [PubMed] [Google Scholar]

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