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. 1982 Feb;23(2):89–97. doi: 10.1136/gut.23.2.89

Diagnosis of oesophageal spasm by ergometrine provocation.

H A Davies, M D Kaye, J Rhodes, A M Dart, A H Henderson
PMCID: PMC1419545  PMID: 7068041

Abstract

Oesophageal spasm may mimic the pain of myocardial ischaemia. Forty-two patients who were thought to have angina until investigations failed to show any cardiovascular abnormality, were examined for oesophageal disease. Ergometrine provocation during oesophageal manometry caused significant deterioration in oesophageal motility, associated with familiar pain, in 24 patients. Ten age-matched controls were examined in a similar way and ergometrine produced motility changes in four and pain in two. Six volunteers with coronary artery stenosis and exercise-induced angina did not develop oesophageal motility changes during the pain. Ergometrine provocation is useful in establishing the diagnosis of oesophageal spasm in patients with recurrent angina-like pain but no cardiac abnormality.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arndorfer R. C., Stef J. J., Dodds W. J., Linehan J. H., Hogan W. J. Improved infusion system for intraluminal esophageal manometry. Gastroenterology. 1977 Jul;73(1):23–27. [PubMed] [Google Scholar]
  2. Bennett J. R., Atkinson M. The differentiation between oesophageal and cardiac pain. Lancet. 1966 Nov 19;2(7473):1123–1127. doi: 10.1016/s0140-6736(66)92209-4. [DOI] [PubMed] [Google Scholar]
  3. Brand D. L., Martin D., Pope C. E., 2nd Esophageal manometrics in patients with angina-like chest pain. Am J Dig Dis. 1977 Apr;22(4):300–304. doi: 10.1007/BF01072186. [DOI] [PubMed] [Google Scholar]
  4. Buxton A., Goldberg S., Hirshfeld J. W., Wilson J., Mann T., Williams D. O., Overlie P., Oliva P. Refractory ergonovine-induced coronary vasospasm: importance of intracoronary nitroglycerin. Am J Cardiol. 1980 Aug;46(2):329–334. doi: 10.1016/0002-9149(80)90080-6. [DOI] [PubMed] [Google Scholar]
  5. Dart A. M., Davies H. A., Dalal J., Ruttley M., Henderson A. H. 'Angina' and normal coronary arteriograms: a follow-up study. Eur Heart J. 1980 Apr;1(2):97–100. doi: 10.1093/oxfordjournals.eurheartj.a061112. [DOI] [PubMed] [Google Scholar]
  6. Dart A. M., Davies H. A., Lowndes R. H., Dalal J., Ruttley M., Henderson A. H. Oesophageal spasm and angina: diagnostic value of ergometrine (ergonovine) provocation. Eur Heart J. 1980 Apr;1(2):91–95. doi: 10.1093/oxfordjournals.eurheartj.a061111. [DOI] [PubMed] [Google Scholar]
  7. Delmonico J. E., Jr, Black A., Gensini G. G. Diaphragmatic hiatal hernia and angina pectoris. Dis Chest. 1968 Mar;53(3):309–315. doi: 10.1378/chest.53.3.309. [DOI] [PubMed] [Google Scholar]
  8. Heupler F. A., Jr Provocative testing for coronary arterial spasm: risk, method and rationale. Am J Cardiol. 1980 Aug;46(2):335–337. doi: 10.1016/0002-9149(80)90081-8. [DOI] [PubMed] [Google Scholar]
  9. Ockene I. S., Shay M. J., Alpert J. S., Weiner B. H., Dalen J. E. Unexplained chest pain in patients with normal coronary arteriograms: a follow-up study of functional status. N Engl J Med. 1980 Nov 27;303(22):1249–1252. doi: 10.1056/NEJM198011273032201. [DOI] [PubMed] [Google Scholar]
  10. Orlando R. C., Bozymski E. M. The effects of pentagastrin in achalasia and diffuse esophageal spasm. Gastroenterology. 1979 Sep;77(3):472–477. [PubMed] [Google Scholar]
  11. RUBIN J., NAGLER R., SPIRO H. M., PILOT M. L. Measuring the effect of emotions on esophageal motility. Psychosom Med. 1962 Mar-Apr;24:170–176. doi: 10.1097/00006842-196203000-00007. [DOI] [PubMed] [Google Scholar]
  12. Waters D. D., Theroux P., Szlachcic J., Dauwe F., Crittin J., Bonan R., Mizgala H. F. Ergonovine testing in a coronary care unit. Am J Cardiol. 1980 Dec 1;46(6):922–930. doi: 10.1016/0002-9149(80)90346-x. [DOI] [PubMed] [Google Scholar]

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