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. 1982 Oct;23(10):854–861. doi: 10.1136/gut.23.10.854

Gut hormone release after intestinal resection.

H S Besterman, T E Adrian, C N Mallinson, N D Christofides, D L Sarson, A Pera, L Lombardo, R Modigliani, S R Bloom
PMCID: PMC1419819  PMID: 7117905

Abstract

To investigate the possible role of gut and pancreatic hormones in the adaptive responses to gut resection, plasma concentrations of the circulating hormones were measured, in response to a test breakfast, in patients with either small or large intestinal resection and in healthy control subjects. In 18 patients with partial ileal resection a significant threefold rise was found in basal and postprandial levels of pancreatic polypeptide, a fourfold increase in motilin, and more than a twofold increase in gastrin and enteroglucagon levels compared with healthy controls. In contrast, nine patients with colonic resection had a threefold rise in levels of pancreatic polypeptide only. One or more of these peptides may have a role in stimulating the adaptive changes found after gut resection.

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Selected References

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