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. 1983 Oct;24(10):909–913. doi: 10.1136/gut.24.10.909

Histochemical changes in mucus in duodenal ulceration.

S M Morrissey, P M Ward, A P Jayaraj, F I Tovey, C G Clark
PMCID: PMC1420154  PMID: 6618270

Abstract

In duodenal ulceration the Alcian blue staining acid mucosubstances in goblet cells are reduced and the goblet cells themselves disappear. At the same time periodic acid-Schiff (PAS) staining neutral mucosubstances appear in the cells of the surface epithelium. These changes have been measured quantitatively with the help of a Vickers M86/0010 Scanning and Integrated Microdensitometer. During healing the changes are reversed. It is suggested that these changes suggest a metaplasia towards a gastric type mucosa as a protective response to the presence of ulceration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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