Skip to main content
Gut logoLink to Gut
. 1984 Dec;25(12):1414–1415. doi: 10.1136/gut.25.12.1414

Recurrent jaundice caused by recurrent hyperemesis gravidarum.

D Larrey, B Rueff, G Feldmann, C Degott, G Danan, J P Benhamou
PMCID: PMC1420189  PMID: 6510771

Abstract

The existence of jaundice induced by hyperemesis gravidarum is controversial. We report the case of a woman who suffered from three episodes of jaundice during the first trimester of three consecutive pregnancies, a few days after the onset of hyperemesis gravidarum. Jaundice was caused by conjugated hyperbilirubinaemia. Serum alanine aminotransferase activity was increased and scarce necrotic hepatocytes were shown on light and electron microscopic examinations. Cessation of vomiting was rapidly followed by complete recovery. This observation supports the view that severe vomiting can cause jaundice in pregnant women.

Full text

PDF
1414

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams R. H., Gordon J., Combes B. Hyperemesis gravidarum. I. Evidence of hepatic dysfunction. Obstet Gynecol. 1968 May;31(5):659–664. [PubMed] [Google Scholar]
  2. Holzbach R. T. Jaundice in pregnancy--1976. Am J Med. 1976 Sep;61(3):367–376. doi: 10.1016/0002-9343(76)90374-0. [DOI] [PubMed] [Google Scholar]
  3. IBER F. L. JAUNDICE IN PREGNANCY--A REVIEW. Am J Obstet Gynecol. 1965 Mar 1;91:721–753. [PubMed] [Google Scholar]
  4. KLIER E. Ikterus im Rahmen der Schwangerschaftsfrühtoxikose. Wien Klin Wochenschr. 1956 Jan 27;68(4):64–66. [PubMed] [Google Scholar]
  5. MEYER J. Ikterus und Schwangerschaft. Geburtshilfe Frauenheilkd. 1955 Nov;15(11):1013–1019. [PubMed] [Google Scholar]
  6. Mahu J. L., Duvaldestin P., Dhumeaux D., Berthelot P. Biliary transport of cholephilic dyes: evidence for two different pathways. Am J Physiol. 1977 May;232(5):E445–E450. doi: 10.1152/ajpendo.1977.232.5.E445. [DOI] [PubMed] [Google Scholar]
  7. THORLING L. Jaundice in pregnancy; a clinical study. Acta Med Scand Suppl. 1955;302:1–123. [PubMed] [Google Scholar]
  8. Verdy M. BSP retention during total fasting. Metabolism. 1966 Sep;15(9):769–772. doi: 10.1016/0026-0495(66)90168-5. [DOI] [PubMed] [Google Scholar]
  9. Webber B. L., Freiman I. The liver in kwashiorkor. A clinical and electron microscopical study. Arch Pathol. 1974 Dec;98(6):400–408. [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES