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. 1980 Mar;21(3):181–186. doi: 10.1136/gut.21.3.181

Comparison of ranitidine and cimetidine in the inhibition of histamine, sham-feeding, and meal-induced gastric secretion in duodenal ulcer patients.

S J Konturek, W Obtulowicz, N Kwiecien, E Sito, E Mikos, J Oleksy
PMCID: PMC1420343  PMID: 6105116

Abstract

The effects of ranitidine, a new H2-receptor antagonist which does not contain an imidazole ring, and cimetidine have been determined on histamine, meal-induced gastric acid secretion, and serum gastrin levels in duodenal ulcer patients. Compared with cimetidine, ranitidine was found to be about eight times more potent an inhibitor of histamine-induced secretion and four to five times more potent an inhibitor of sham-feeding, and real feeding induced acid secretion without effecting serum gastrin levels.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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