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. 1980 Mar;21(3):192–194. doi: 10.1136/gut.21.3.192

Hydrolysis of pyridoxal-5'-phosphate in plasma in conditions with raised alkaline phosphate.

B B Anderson, H O'Brien, G E Griffin, D L Mollin
PMCID: PMC1420355  PMID: 7399318

Abstract

Hydrolysis of pyridoxal phosphate in plasma was demonstrated in patients with liver disease and other conditions with raised alkaline phosphatase, and this usually closely paralleled the alkaline phosphatase level, whether of liver or bone origin. The endogenous plasma pyridoxal phosphate was inversely related to the alkaline phosphatase, and plasma hydrolysis of pyridoxal phosphate may at least in part be responsible. Very large doses of vitamin B6 may be necessary to compensate for this hydrolysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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