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. 1993 May;79(1):171–173.

Prediction of an HLA B8-restricted influenza epitope by motif.

A Suhrbier 1, C Schmidt 1, A Fernan 1
PMCID: PMC1422045  PMID: 7685314

Abstract

Alignment of previously identified HLA B8-restricted cytotoxic T-cell (CTL) epitopes revealed a common motif: x, x, K/R, x, R/K, x, W/Y, x, I/L. Of five motif-conforming peptides tested, ELRSRYWAI was found to represent a new epitope from influenza nucleoprotein (NP). High concentrations of some peptides gave cross-reactive stimulation illustrating the requirement to confirm epitope assignment with recombinant vaccinias and highlighting a potential problem of peptide-based CTL vaccines.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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