Skip to main content
Immunology logoLink to Immunology
. 1973 May;24(5):823–830.

An in vivo primary response to 2,4,6-trinitrophenyl substituted erythrocytes

T L Pazdernik, E M Uyeki
PMCID: PMC1422804  PMID: 4577080

Abstract

Cell kinetics of the 2,4,6-trinitrophenyl (TNP)-erythrocyte response in non-immune, immune, and vinblastine-treated immune BDF1 mice were studied by measuring hapten- and carrier-RFC and hapten- and carrier-PFC responses at various time intervals. Injection of a single dose of horse red blood cells alone enhances the anti-TNP response.

Full text

PDF
823

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brody T. Identification of two cell populations required for mouse immunocompetence. J Immunol. 1970 Jul;105(1):126–138. [PubMed] [Google Scholar]
  2. Chiller J. M., Weigle W. O. Plaque forming cells to 2,-4 dinitrophenyl in spleens of immunized and nonimmunized mice. Immunochemistry. 1970 Dec;7(12):989–992. doi: 10.1016/0019-2791(70)90005-4. [DOI] [PubMed] [Google Scholar]
  3. Haskill J. S., Harbrook J. In vitro immunity to sheep erythrocytes by fractionated spleen cells: differentiation within the antibody-forming-cell precursor population. Cell Immunol. 1972 Mar;3(3):448–460. doi: 10.1016/0008-8749(72)90250-x. [DOI] [PubMed] [Google Scholar]
  4. Jormalainen S., Mäkelä O. Anti-hapten antibodies in normal sera. Eur J Immunol. 1971 Dec;1(6):471–478. doi: 10.1002/eji.1830010613. [DOI] [PubMed] [Google Scholar]
  5. Kettman J., Dutton R. W. An in vitro primary immune response to 2,4,6-trinitrophenyl substituted erythrocytes: response against carrier and hapten. J Immunol. 1970 Jun;104(6):1558–1561. [PubMed] [Google Scholar]
  6. McConnell I., Munro A., Gurner B. W., Coombs R. R. Studies on actively allergized cells. I. The cyto-dynamics and morphology of rosete-forming lymph node cells in mice and inhibition of rosette-formation with antibody to mouse immunoglobulins. Int Arch Allergy Appl Immunol. 1969;35(3):209–227. [PubMed] [Google Scholar]
  7. McConnell I. Studies on actively allergised cells. 3. Suppression of the allergic response with specific antibody and the effect of this treatment on plaque and rosette-forming cells. Int Arch Allergy Appl Immunol. 1971;40(2):287–304. [PubMed] [Google Scholar]
  8. McNeill T. A. Antigenic stimulation of bone marrow colony forming cells. I. Effect of antigens on normal bone marrow cells in vitro. Immunology. 1970 Jan;18(1):39–47. [PMC free article] [PubMed] [Google Scholar]
  9. Mishell R. I., Dutton R. W. Immunization of dissociated spleen cell cultures from normal mice. J Exp Med. 1967 Sep 1;126(3):423–442. doi: 10.1084/jem.126.3.423. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Osoba D. Some physical and radiobiological properties of immunologically reactive mouse spleen cells. J Exp Med. 1970 Aug 1;132(2):368–383. doi: 10.1084/jem.132.2.368. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Rittenberg M. B., Pratt K. L. Antitrinitrophenyl (TNP) plaque assay. Primary response of Balb/c mice to soluble and particulate immunogen. Proc Soc Exp Biol Med. 1969 Nov;132(2):575–581. doi: 10.3181/00379727-132-34264. [DOI] [PubMed] [Google Scholar]
  12. Sterzl J., Ríha I. Detection of cells producing 7S antibodies by the plaque technique. Nature. 1965 Nov 27;208(5013):858–859. doi: 10.1038/208858a0. [DOI] [PubMed] [Google Scholar]
  13. Uyeki E. M. Effect of antibiotics on the development of antibody-producing cells, in vitro. Biochem Pharmacol. 1972 Jan;21(1):59–68. doi: 10.1016/0006-2952(72)90250-x. [DOI] [PubMed] [Google Scholar]
  14. Uyeki E. M., Llacer V. Effect of antibiotics on antibody-forming cells in vitro. Biochem Pharmacol. 1969 Apr;18(4):948–951. doi: 10.1016/0006-2952(69)90074-4. [DOI] [PubMed] [Google Scholar]

Articles from Immunology are provided here courtesy of British Society for Immunology

RESOURCES