Abstract
ECF-A and C5a were chemotactic both for eosinophils and neutrophils. However, when eosinophils comprised approximately 10 per cent or more of a mixed leucocyte population, they were preferentially attracted by both of these agents.
Marked synergism was observed between ECF-A and C5a in their ability to attract eosinophil leucocytes.
Full text
PDF







Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cook C. T., Shin H. S., Mayer M. M., Laudenslayer K. A. The fifth component of the guinea pig complement system. I. Purification and characterization. J Immunol. 1971 Feb;106(2):467–472. [PubMed] [Google Scholar]
- Kay A. B., Austen K. F. Chemotaxis of human basophil leucocytes. Clin Exp Immunol. 1972 Aug;11(4):557–563. [PMC free article] [PubMed] [Google Scholar]
- Kay A. B., Stechschulte D. J., Austen K. F. An eosinophil leukocyte chemotactic factor of anaphylaxis. J Exp Med. 1971 Mar 1;133(3):602–619. doi: 10.1084/jem.133.3.602. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shin H. S., Snyderman R., Friedman E., Mellors A., Mayer M. M. Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. Science. 1968 Oct 18;162(3851):361–363. doi: 10.1126/science.162.3851.361. [DOI] [PubMed] [Google Scholar]
- Snyderman R., Shin H. S., Hausman M. H. A chemotactic factor for mononuclear leukocytes. Proc Soc Exp Biol Med. 1971 Nov;138(2):387–390. doi: 10.3181/00379727-138-35903. [DOI] [PubMed] [Google Scholar]
- Ward P. A., Newman L. J. A neutrophil chemotactic factor from human C'5. J Immunol. 1969 Jan;102(1):93–99. [PubMed] [Google Scholar]
