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. 1974 Jun;26(6):1115–1125.

Depressed responses of the granulocyte—macrophage system to bacterial antigens following preimmunization*

D Metcalf
PMCID: PMC1423366  PMID: 4604301

Abstract

Injection of C57B1 mice with endotoxin or other bacterial antigens normally produces (i) a rise in the serum level of a factor that stimulates granulocyte and macrophage colony formation in vitro and (ii) a rise in the numbers of granulocyte and macrophage progenitors in the blood. Preinjection of the mice with polymerized flagellins of Salmonella species specifically depressed both types of response. After a single injection of flagellin, depressed responsiveness began within 24 hr, persisted for several months and could be passively transferred to normal mice by injection of immune serum. Responsiveness was partially restored by 850 R whole body irradiation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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