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. 1981 Jul-Aug;96(4):350–356.

Increased leukemia, lymphoma, and spontaneous abortion in Western New York following a flood disaster.

D T Janerich, A D Stark, P Greenwald, W S Burnett, H I Jacobson, J McCusker
PMCID: PMC1424239  PMID: 7255659

Abstract

The New York State Department of Health was asked in September 1978 of investigate a cluster of leukemias and lymphomas in a rural town in western New York State of less than 1,000 people. Four cases of these diseases had been diagnosed in the town's population in the previous 10 months. Residents were concerned about environmental hazards such as background radiation and contamination of their water supply. A total environmental study of the area was not feasible or warranted, but certain environmental studies of the area were conducted. No environmental health hazards were identified. Incidence rates for towns in the four-county area (population 281,000) surrounding the study town were analyzed, based on data from the New York State Cancer Registry. These four counties had been severely affected by the flood following the 1972 Hurricane Agnes. Examination of annual leukemia and lymphoma incidence rates for these counties for 1966--77 revealed that the rates for towns in the river valley (population 102,000), but not for nonriver-valley towns, were 20 to 50 percent above the statewide rates for 1972--77. All other cancer rates remained level throughout both periods. An analysis of spontaneous abortion rates for the four counties for 1968--77 showed a significant peak in 1973, but not for the rest of upstate New York. The peak was concentrated in the towns in the river valley. The apparent time-space cluster of leukemias and lymphomas in conjunction with a marked increase in the spontaneous abortion rate suggests an unidentified flood-related environmental exposure.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blair A., Thomas T. L. Leukemia among Nebraska farmers: a death certificate study. Am J Epidemiol. 1979 Sep;110(3):264–273. doi: 10.1093/oxfordjournals.aje.a112811. [DOI] [PubMed] [Google Scholar]
  2. Corson S. A. Physiologic responses to avoidable and unavoidable psychologic stress in relation to genetic differences. Ann N Y Acad Sci. 1969 Oct 14;164(2):526–534. doi: 10.1111/j.1749-6632.1969.tb14070.x. [DOI] [PubMed] [Google Scholar]
  3. Dean A., Lin N. The stress-buffering role of social support. Problems and prospects for systematic investigation. J Nerv Ment Dis. 1977 Dec;165(6):403–417. doi: 10.1097/00005053-197712000-00006. [DOI] [PubMed] [Google Scholar]
  4. GENTRY J. T., PARKHURST E., BULIN G. V., Jr An epidemiological study of congenital malformations in New York State. Am J Public Health Nations Health. 1959 Apr;49(4):497–513. doi: 10.2105/ajph.49.4.497. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Greene W. A., Swisher S. N. Psychological and somatic variables associated with the development and course of monozygotic twins discordant for leukemia. Ann N Y Acad Sci. 1969 Oct 14;164(2):394–408. doi: 10.1111/j.1749-6632.1969.tb14053.x. [DOI] [PubMed] [Google Scholar]
  6. Greene W. A. The psychosocial setting of the development of leukemia and lymphoma. Ann N Y Acad Sci. 1966 Jan 21;125(3):794–801. doi: 10.1111/j.1749-6632.1966.tb45428.x. [DOI] [PubMed] [Google Scholar]
  7. Greenwald P., Rose J. S., Daitch P. B. Acquaintance networks among leukemia and lymphoma patients. Am J Epidemiol. 1979 Aug;110(2):162–177. doi: 10.1093/oxfordjournals.aje.a112801. [DOI] [PubMed] [Google Scholar]
  8. Logue J. N., Hansen H., Struening E. Emotional and physical distress following Hurricane Agnes in Wyoming Valley of Pennsylvania. Public Health Rep. 1979 Nov-Dec;94(6):495–502. [PMC free article] [PubMed] [Google Scholar]
  9. Milham S., Jr, Hesser J. E. Hodgkin's disease in woodworkers. Lancet. 1967 Jul 15;2(7507):136–137. doi: 10.1016/s0140-6736(67)92969-8. [DOI] [PubMed] [Google Scholar]
  10. Rabkin J. G., Struening E. L. Live events, stress, and illness. Science. 1976 Dec 3;194(4269):1013–1020. doi: 10.1126/science.790570. [DOI] [PubMed] [Google Scholar]
  11. Sklar L. S., Anisman H. Stress and coping factors influence tumor growth. Science. 1979 Aug 3;205(4405):513–515. doi: 10.1126/science.109924. [DOI] [PubMed] [Google Scholar]
  12. Vianna N. J., Greenwald P., Davies J. N. Extended epidemic of Hodgkin's disease in high-school students. Lancet. 1971 Jun 12;1(7711):1209–1211. doi: 10.1016/s0140-6736(71)91719-3. [DOI] [PubMed] [Google Scholar]

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