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. 1982 Dec;14(6):857–860. doi: 10.1111/j.1365-2125.1982.tb02049.x

Oral piretanide in chronic renal failure.

I S Henderson, T J Beattie, A C Kennedy, S L Dombey
PMCID: PMC1427558  PMID: 7150461

Abstract

1 The effects of high doses of piretanide, a new diuretic agent chemically related to frusemide and bumetanide were evaluated in twelve patients with severe chronic renal insufficiency (creatinine clearance below 25 ml/min). 2 Patients received either 30 mg or 60 mg piretanide orally after a water load of 11. Urine volume and the excretion of electrolytes, creatinine, urea and uric acid were measured over the subsequent 24 h. 3 Piretanide produced an effective diuresis and natriuresis in these patients, its action being broadly similar to those of bumetanide and frusemide observed in previous studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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