Abstract
1 The effects of guanfacine, given once daily in dosages of 0.5-3 mg, on blood pressure and lung function were investigated in a placebo controlled single-blind trial in 10 patients with hypertension and chronic obstructive lung disease.
2 Six of the 10 patients also received a thiazide diuretic in an unchanged dose throughout the study.
3 Guanfacine lowered diastolic blood pressure to less than 95 mm Hg in 9/10 patients.
4 Lung function was not influenced by guanfacine.
5 A dry mouth was the most frequent side effect.
Keywords: guanfacine, lung function, hypertension, asthma
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Selected References
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