Abstract
A special clinic was set up in an attempt to overcome the problem of accumulating a sufficient number of depressed patients for inclusion in clinical trials. Only 21 patients of the 81 patients referred during 1 year fulfilled the criteria for inclusion in the trials. The function of the special clinic did not prove successful as a similar proportion of depressed patients was found in a comparison group referred to the district psychiatric outpatient clinic.
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Selected References
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- Blackwell B., Shepherd M. Early evaluation of psychotropic drugs in man. A trial that failed. Lancet. 1967 Oct 14;2(7520):819–822. doi: 10.1016/s0140-6736(67)92250-7. [DOI] [PubMed] [Google Scholar]
- Jenner F. A. Some of the problems and difficulties associated with clinical studies of antidepressant agents. Br J Clin Pharmacol. 1977;4(Suppl 2):199S–207S. doi: 10.1111/j.1365-2125.1977.tb05753.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Little J. C., Kerr T. A., McClelland H. A. Where are the untreated depressives? Br Med J. 1978 Jun 17;1(6127):1593–1594. doi: 10.1136/bmj.1.6127.1593-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Snaith R. P., Ahmed S. N., Mehta S., Hamilton M. Assessment of the severity of primary depressive illness. Wakefield self-assessment depression inventory. Psychol Med. 1971 Feb;1(2):143–149. doi: 10.1017/s0033291700000064. [DOI] [PubMed] [Google Scholar]