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British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1983 Aug;16(2):188–190. doi: 10.1111/j.1365-2125.1983.tb04984.x

Lack of evidence for polymorphism in metoprolol metabolism.

D B Jack, M Wilkins, C P Quarterman
PMCID: PMC1427977  PMID: 6615692

Abstract

The claim for polymorphism in the metabolism of metoprolol is based on a logical fallacy. A frequency distribution of metoprolol AUC data is presented and, although highly skewed, no evidence of more than a single population is apparent. Plasma and urine metoprolol and metabolite data are also presented to support this.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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