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. 1983;16(Suppl 1):157S–160S. doi: 10.1111/j.1365-2125.1983.tb02288.x

Hypnotic efficacy and safety of midazolam and oxazepam in hospitalized female patients

R Fischbach
PMCID: PMC1428083  PMID: 6138070

Abstract

1 This double-blind study in 60 hospitalized female patients comparing midazolam 15 mg, oxazepam 15 mg and placebo, demonstrated an inter-group difference in favour of midazolam with regard to efficacy.

2 The sleep parameters of onset latency and duration were improved by midazolam.

3 All three compounds were very well tolerated and no withdrawal symptoms were observed.

4 Midazolam, in an oral dose of 15 mg, can thus be regarded as an effective, well-tolerated agent for the treatment of sleep disorders.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amrein R., Cano J. P., Eckert M., Coassolo P. Pharmakokinetik von Midazolam nach intravenöser Verabreichung. Arzneimittelforschung. 1981;31(12A):2202–2205. [PubMed] [Google Scholar]
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