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. 1976 Oct;3(5):843–848. doi: 10.1111/j.1365-2125.1976.tb00636.x

Modification by diazepam or thioridazine of the psychomotor skills related to driving: a subacute trial in neurotic out-patients.

I Saario, M Linnoila, M J Mattila
PMCID: PMC1428934  PMID: 973981

Abstract

Forty-five out-patients with clinically manifested anxiety were tested in order to study the effects of 2 weeks' treatment with placebo, diazepam (5-10 mg three times daily) or thioridazine (25-50 mg three times daily) on their psychomotor skills related to driving. When compared with placebo, diazepam increased the number of mistakes in reaction and co-ordination tests and also decreased ability to discriminate the fusion of flickering light. When compared to other groups, reactive and co-ordinative skills were more impaired in patients treated with thioridazine which also impaired divided attention. Aubjectively thioridazine was not experienced as effective an anxiolytic as diazepam.

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Selected References

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