Abstract
1 A rapid simple gas chromatographic technique for determining nomifensine in plasma is described.
2 Nomifensine is rapidly absorbed after oral administration to man.
3 Following a 100-mg dose, peak levels of an acid-labile conjugate of 2—3 μg/ml are reached about 1.5 h after administration.
4 The conjugate is cleared with a half-life of between 1 and 2 hours.
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