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British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1979;8(Suppl 1):73S–77S. doi: 10.1111/j.1365-2125.1979.tb00461.x

Double-blind evaluation of the efficacy and safety of temazepam in outpatients with insomnia

J M Fillingim
PMCID: PMC1429622  PMID: 41546

Abstract

1 The efficacy and safety of temazepam 30 mg, compared with glutethimide 500 mg and placebo, were evaluated in double-blind conditions in a 4-day study in 75 outpatients with a history of insomnia.

2 Temazepam and glutethimide were rated by the patients as effective and significantly superior to placebo for general quality of sleep, time required to fall asleep, frequency of nocturnal and early morning awakenings, and duration of sleep.

3 Residual effects reported for temazepam and glutethimide immediately after awakening and during the day were similar to or less than those reported for placebo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Jinks M. Insomnia and its treatment. J Am Pharm Assoc. 1976 Nov;16(11):613–616. [PubMed] [Google Scholar]

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