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. 1979 Dec;8(6):581–587. doi: 10.1111/j.1365-2125.1979.tb01048.x

Comparison of propranolol and metoprolol in the management of hyperthyroidism.

L E Murchison, J How, P D Bewsher
PMCID: PMC1429912  PMID: 391258

Abstract

1 Propranolol and metoprolol were both effective in controlling the symptoms and signs of hyperthyroidism. 2 Propranolol caused a highly significant increase in serum reverse T3 concentrations with lesser changes in other serum thyroid hormone levels, whereas metoprolol did not have this effect. 3 Steady-state plasma propranolol and metoprolol levels showed marked inter-individual variation. Metoprolol concentrations showed relatively little intra-individual variability, and could be related to the clinical efficacy of the drug, whereas no such relationship was demonstrated for propranolol.

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Selected References

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