Profiling of Hodgkin’s Lymphoma Cell Line L1236 and Germinal Center B Cells: Identification of Hodgkin’s Lymphoma-specific Genes
Ines Schwering, Andreas Bräuninger, Verena Distler, Julia Jesdinsky, Volker Diehl, Martin-Leo Hansmann, Klaus Rajewsky, and Ralf Küppers
Mol Med 9:85–95.
The tag numbers, given for the genes downregulated in the HL cell line L1236 compared with centroblasts, in Table 1 and on p 89 erroneously corresponded to small profiles (20500 tags) instead of the final profiles of around 30000 tags. The correct tag numbers for a profile of 30000 tags are available on http://www.bloodjournal.org/cgi/content/full/101/4/1505/DC1 by searching for the tag sequences.
In the list of the 20 transcripts displaying the largest decrease in expression (Table 1) in a profile with 30000 tags, 3 tags have to be exchanged (AAACCAGAGG, ACTTTTTCAA, TTAAATCCCA are excluded and ACTTCCTTCC [ionotropic ATP receptor], GACTTTTCTG [oct-binding factor], and CCTCCTTCCT [IgM and IgD heavy chain genes] are included).
In the paragraph “Identification of downregulated transcripts in L1236” on p 89, the correct numbers of fold-downregulation should read: “...of G-protein signaling 13, a negative regulator of G-protein signaling that is 17-fold downregulated...,” “...regulator of G-protein signaling 5 (16-fold)...,” and “...namely rho GDP dissociation inhibitor (GDI)α (3-fold) and rho(GDI)β (7-fold).”
The authors regret the error.