Abstract
The histopathological features and results of treatment of malignant polyps removed by endoscopic polypectomy from 60 patients are presented. The patients were followed for a minimum of five years. Forty six patients were treated by polypectomy alone as local excision was judged complete and the invasive carcinoma was well or moderately well differentiated. Thirty seven of these patients are alive and well after five years and the remaining nine have died of other causes up to four years later: there was no evidence of recurrence in any of these cases. Fourteen patients underwent a subsequent major surgical resection and residual tumour was found at the site of polypectomy in two cases but regional lymph nodes were not involved. Only one patient from this group with a high grade tumour developed metastases although the operative specimen was free of tumour. Malignant polyps can be successfully treated by polypectomy alone provided both the laboratory techniques of examination and the histopathological criteria are strictly applied.
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- Colacchio T. A., Forde K. A., Scantlebury V. P. Endoscopic polypectomy: inadequate treatment for invasive colorectal carcinoma. Ann Surg. 1981 Dec;194(6):704–707. doi: 10.1097/00000658-198112000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cooper H. S. Surgical pathology of endoscopically removed malignant polyps of the colon and rectum. Am J Surg Pathol. 1983 Oct;7(7):613–623. doi: 10.1097/00000478-198310000-00002. [DOI] [PubMed] [Google Scholar]
- Fenoglio C. M., Kaye G. I., Lane N. Distribution of human colonic lymphatics in normal, hyperplastic, and adenomatous tissue. Its relationship to metastasis from small carcinomas in pedunculated adenomas, with two case reports. Gastroenterology. 1973 Jan;64(1):51–66. [PubMed] [Google Scholar]
- Gillespie P. E., Chambers T. J., Chan K. W., Doronzo F., Morson B. C., Williams C. B. Colonic adenomas--a colonoscopy survey. Gut. 1979 Mar;20(3):240–245. doi: 10.1136/gut.20.3.240. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morson B. C., Bussey H. J., Samoorian S. Policy of local excision for early cancer of the colorectum. Gut. 1977 Dec;18(12):1045–1050. doi: 10.1136/gut.18.12.1045. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morson B. C. Factors influencing the prognosis of early cancer of the rectum. Proc R Soc Med. 1966 Jul;59(7):607–608. doi: 10.1177/003591576605900710. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Williams C., Muto T., Rutter K. R. Removal of polyps with fibreoptic colonoscope: a new approach to colonic polypectomy. Br Med J. 1973 Feb 24;1(5851):451–452. doi: 10.1136/bmj.1.5851.451. [DOI] [PMC free article] [PubMed] [Google Scholar]