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. 1985 Jun;26(6):544–549. doi: 10.1136/gut.26.6.544

Diet and other factors in the aetiology of diverticulosis: an epidemiological study in Greece.

O Manousos, N E Day, A Tzonou, C Papadimitriou, A Kapetanakis, A Polychronopoulou-Trichopoulou, D Trichopoulos
PMCID: PMC1432747  PMID: 3924745

Abstract

A case control study exploring the role of diet and other biosocial factors in the aetiology of diverticulosis was undertaken in Athens, Greece, in 1981-1982. One hundred consecutive cases with radiologically confirmed diverticulosis and 110 control patients with fractures or other orthopaedic disorders were submitted to a structured interview, including frequency of consumption of about 80 food items. The main positive findings were, (i) the cases reported significantly less frequent consumption of vegetables, brown bread and, to a lesser extent, potatoes and fruits, and (ii) the cases reported significantly more frequent consumption of meat and, to a lesser extent, milk, and milk products. The difference in risk between those people who frequently consume vegetables but rarely consume meat, and those who rarely consume vegetables and frequently consume meat, was almost 50-fold.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Almy T. P., Howell D. A. Medical progress. Diverticular disease of the colon. N Engl J Med. 1980 Feb 7;302(6):324–331. doi: 10.1056/NEJM198002073020605. [DOI] [PubMed] [Google Scholar]
  2. Archampong E. Q., Christian F., Badoe E. A. Diverticular disease in an indigenous African community. Ann R Coll Surg Engl. 1978 Nov;60(6):464–470. [PMC free article] [PubMed] [Google Scholar]
  3. Brodribb A. J., Humphreys D. M. Diverticular disease: three studies. Part I--Relation to other disorders and fibre intake. Br Med J. 1976 Feb 21;1(6007):424–425. doi: 10.1136/bmj.1.6007.424. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Brodribb A. J. Treatment of symptomatic diverticular disease with a high-fibre diet. Lancet. 1977 Mar 26;1(8013):664–666. doi: 10.1016/s0140-6736(77)92112-2. [DOI] [PubMed] [Google Scholar]
  5. CARLSON A. J., HOELZEL F. Relation of diet to diverticulosis of the colon in rats. Gastroenterology. 1949 Jan;12(1):108–115. [PubMed] [Google Scholar]
  6. Davey W. W. Diet and diverticulitis. Br Med J. 1968 Jan 13;1(5584):118–118. doi: 10.1136/bmj.1.5584.118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Garry R. C. Diet and diverticulosis. Br Med J. 1971 Jun 26;2(5764):773–773. doi: 10.1136/bmj.2.5764.773-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Gear J. S., Ware A., Fursdon P., Mann J. I., Nolan D. J., Brodribb A. J., Vessey M. P. Symptomless diverticular disease and intake of dietary fibre. Lancet. 1979 Mar 10;1(8115):511–514. doi: 10.1016/s0140-6736(79)90942-5. [DOI] [PubMed] [Google Scholar]
  9. Graham S., Dayal H., Swanson M., Mittelman A., Wilkinson G. Diet in the epidemiology of cancer of the colon and rectum. J Natl Cancer Inst. 1978 Sep;61(3):709–714. [PubMed] [Google Scholar]
  10. Manousos O. N., Truelove S. C., Lumsden K. Transit times of food in patients with diverticulosis or irritable colon syndrome and normal subjects. Br Med J. 1967 Sep 23;3(5568):760–762. doi: 10.1136/bmj.3.5568.760. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Manousos O. N., Vrachliotis G., Papaevangelou G., Detorakis E., Doritis P., Stergiou L., Merikas G. Relation of diverticulosis of the colon to environmental factors in Greece. Am J Dig Dis. 1973 Mar;18(3):174–176. doi: 10.1007/BF01071969. [DOI] [PubMed] [Google Scholar]
  12. Manousos O., Day N. E., Trichopoulos D., Gerovassilis F., Tzonou A., Polychronopoulou A. Diet and colorectal cancer: a case-control study in Greece. Int J Cancer. 1983 Jul 15;32(1):1–5. doi: 10.1002/ijc.2910320102. [DOI] [PubMed] [Google Scholar]
  13. Mendeloff A. I. A critique of "fiber deficiency". Am J Dig Dis. 1976 Feb;21(2):109–112. doi: 10.1007/BF01072053. [DOI] [PubMed] [Google Scholar]
  14. Miettinen O. Estimability and estimation in case-referent studies. Am J Epidemiol. 1976 Feb;103(2):226–235. doi: 10.1093/oxfordjournals.aje.a112220. [DOI] [PubMed] [Google Scholar]
  15. Ornstein M. H., Littlewood E. R., Baird I. M., Fowler J., North W. R., Cox A. G. Are fibre supplements really necessary in diverticular disease of the colon? A controlled clinical trial. Br Med J (Clin Res Ed) 1981 Apr 25;282(6273):1353–1356. doi: 10.1136/bmj.282.6273.1353. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Painter N. S., Burkitt D. P. Diverticular disease of the colon: a deficiency disease of Western civilization. Br Med J. 1971 May 22;2(5759):450–454. doi: 10.1136/bmj.2.5759.450. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Thompson W. G., Patel D. G., Tao H., Nair R. C. Does uncomplicated diverticular disease produce symptoms? Dig Dis Sci. 1982 Jul;27(7):605–608. doi: 10.1007/BF01297216. [DOI] [PubMed] [Google Scholar]

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