Skip to main content
NCBI home page
Gut logoLink to Gut
. 1987 Jun;28(6):694–700. doi: 10.1136/gut.28.6.694

[14C]-triolein absorption: a useful test in the diagnosis of malabsorption.

J M Turner, S Lawrence, I W Fellows, I Johnson, P G Hill, G K Holmes
PMCID: PMC1433043  PMID: 3623216

Abstract

The [14C]-triolein absorption test has been assessed using a preprepared fat meal in a procedure that can be completed within a working day on an inpatient or outpatient basis. An initial study showed complete discrimination between 30 control subjects and 13 patients with raised faecal fat excretion. A prospective evaluation in 57 patients under investigation for gastrointestinal disease showed a sensitivity of 85% and specificity of 93% (100% if two obese subjects are excluded). The test discriminates satisfactorily between patients with and without fat malabsorption and makes the measurement of faecal fat unnecessary in most circumstances.

Full text

PDF
694

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Akesson B., Florén C. H. Use of the triolein breath test for the demonstration of fat malabsorption in coeliac disease. Scand J Gastroenterol. 1984 May;19(3):307–314. [PubMed] [Google Scholar]
  2. Benini L., Scuro L. A., Menini E., Manfrini C., Vantini I., Vaona B., Brocco G., Talamini G., Cavallini G. Is the 14C-triolein breath test useful in the assessment of malabsorption in clinical practice? Digestion. 1984;29(2):91–97. doi: 10.1159/000199015. [DOI] [PubMed] [Google Scholar]
  3. Einarsson K., Björkhem I., Eklöf R., Blomstrand R. 14C-triolein breath test as a rapid and convenient screening test for fat malabsorption. Scand J Gastroenterol. 1983 Jan;18(1):9–12. doi: 10.3109/00365528309181550. [DOI] [PubMed] [Google Scholar]
  4. Hamilton I., Cobden I., Rothwell J., Axon A. T. Intestinal permeability in coeliac disease: the response to gluten withdrawal and single-dose gluten challenge. Gut. 1982 Mar;23(3):202–210. doi: 10.1136/gut.23.3.202. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hepner G. W. Breath analysis: gastroenterological applications. Gastroenterology. 1974 Dec;67(6):1250–1256. [PubMed] [Google Scholar]
  6. Menzies I. S., Laker M. F., Pounder R., Bull J., Heyer S., Wheeler P. G., Creamer B. Abnormal intestinal permeability to sugars in villous atrophy. Lancet. 1979 Nov 24;2(8152):1107–1109. doi: 10.1016/s0140-6736(79)92507-8. [DOI] [PubMed] [Google Scholar]
  7. Newcomer A. D., Hofmann A. F., DiMagno E. P., Thomas P. J., Carlson G. L. Triolein breath test: a sensitive and specific test for fat malabsorption. Gastroenterology. 1979 Jan;76(1):6–13. [PubMed] [Google Scholar]
  8. Rosenberg I. H., Sitrin M. D. Screening for fat malabsorption. Ann Intern Med. 1981 Dec;95(6):776–777. doi: 10.7326/0003-4819-95-6-776. [DOI] [PubMed] [Google Scholar]
  9. Thorsgaard Pedersen N., Nyboe Andersen B., Marqversen J. Estimation of 14C-triolein assimilation as a test of lipid assimilation. Breath test or measurement of serum radioactivity? Scand J Gastroenterol. 1982 Mar;17(2):309–316. doi: 10.3109/00365528209182059. [DOI] [PubMed] [Google Scholar]
  10. West P. S., Levin G. E., Griffin G. E., Maxwell J. D. Comparison of simple screening tests for fat malabsorption. Br Med J (Clin Res Ed) 1981 May 9;282(6275):1501–1504. doi: 10.1136/bmj.282.6275.1501. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES