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. 1988 Feb;29(2):218–222. doi: 10.1136/gut.29.2.218

Sigmoid motility in diverticular disease and the irritable bowel syndrome.

I F Trotman 1, J J Misiewicz 1
PMCID: PMC1433293  PMID: 3345933

Abstract

Intraluminal pressures were measured with four open ended, water perfused tubes in the fasting state and after a standard liquid meal (400 KCal, 375 ml, protein 15 g, carbohydrate 55 g, lipid 13.4 g) in six patients with sigmoid diverticular disease, 20 with the irritable bowel syndrome and in 13 controls. The pressure sensors were positioned in the true sigmoid colon at colonoscopy at 25, 35, 45, and 55 cm from the anus. Colonic pressures were significantly higher in diverticular disease than in controls before (p less than 0.02) and after the meal (p less than 0.002), some pressure amplitudes exceeding 300 cm H2O. Patients with the irritable bowel syndrome had lower (p less than 0.05) pressures than controls before the meal. Postprandial sigmoid pressures were within the mean +/- 2 SD of controls in 10, above in two and below in eight patients with the irritable bowel. Hypercontractility of the sigmoid colon in the irritable bowel syndrome was not confirmed under the conditions of this study. The association between sigmoid diverticulosis and high intraluminal pressures is confirmed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abrahamsson H., Dotevall G. Effects of propranolol on colonic pressure in patients with irritable bowel syndrome. Scand J Gastroenterol. 1981;16(8):1021–1024. doi: 10.3109/00365528109181022. [DOI] [PubMed] [Google Scholar]
  2. Abrahamsson H., Lyrenäs E., Dotevall G. Effects of beta-adrenoceptor blocking drugs on human sigmoid colonic motility. Dig Dis Sci. 1983 Jul;28(7):590–594. doi: 10.1007/BF01299918. [DOI] [PubMed] [Google Scholar]
  3. Holdstock D. J., Misiewicz J. J., Waller S. L. Observations on the mechanism of abdominal pain. Gut. 1969 Jan;10(1):19–31. doi: 10.1136/gut.10.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Nivatvongs S., Fryd D. S. How far does the proctosigmoidoscope reach? A prospective study of 1000 patients. N Engl J Med. 1980 Aug 14;303(7):380–382. doi: 10.1056/NEJM198008143030707. [DOI] [PubMed] [Google Scholar]
  5. Palmer R. L., Stonehill E., Crisp A. H., Waller S. L., Misiewicz J. J. Psychological characteristics of patients with the irritable bowel syndrome. Postgrad Med J. 1974 Jul;50(585):416–419. doi: 10.1136/pgmj.50.585.416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut. 1973 Feb;14(2):125–132. doi: 10.1136/gut.14.2.125. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Snape W. J., Jr, Carlson G. M., Cohen S. Colonic myoelectric activity in the irritable bowel syndrome. Gastroenterology. 1976 Mar;70(3):326–330. [PubMed] [Google Scholar]
  8. Snape W. J., Jr, Carlson G. M., Matarazzo S. A., Cohen S. Evidence that abnormal myoelectrical activity produces colonic motor dysfunction in the irritable bowel syndrome. Gastroenterology. 1977 Mar;72(3):383–387. [PubMed] [Google Scholar]
  9. Snape W. J., Jr, Wright S. H., Battle W. M., Cohen S. The gastrocolic response: evidence for a neural mechanism. Gastroenterology. 1979 Dec;77(6):1235–1240. [PubMed] [Google Scholar]
  10. Sun E. A., Snape W. J., Jr, Cohen S., Renny A. The role of opiate receptors and cholinergic neurons in the gastrocolonic response. Gastroenterology. 1982 Apr;82(4):689–693. [PubMed] [Google Scholar]
  11. Taylor I., Darby C., Hammond P., Basu P. Is there a myoelectrical abnormality in the irritable colon syndrome? Gut. 1978 May;19(5):391–395. doi: 10.1136/gut.19.5.391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Weinreich J., Andersen D. Intraluminal pressure in the sigmoid colon. II. Patients with sigmoid diverticula and related conditions. Scand J Gastroenterol. 1976;11(6):581–586. [PubMed] [Google Scholar]
  13. Whitehead W. E., Engel B. T., Schuster M. M. Irritable bowel syndrome: physiological and psychological differences between diarrhea-predominant and constipation-predominant patients. Dig Dis Sci. 1980 Jun;25(6):404–413. doi: 10.1007/BF01395503. [DOI] [PubMed] [Google Scholar]

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