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. 1987 Nov;28(11):1517–1521. doi: 10.1136/gut.28.11.1517

Familial giant hypertrophic gastritis (Ménétrier's disease).

B Larsen 1, U Tarp 1, E Kristensen 1
PMCID: PMC1433692  PMID: 3322957

Abstract

Familial giant hypertrophic gastritis involving three generations is reported. A review of the literature, where approximately 200 cases are described, showed only few cases of familial occurrence of this disease, and only in siblings. Our findings suggest dominant heredity, but considering the sparsity of familial occurrence reported earlier, heredity seems to be of only minor pathogenetic significance.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CATANZARO C., WEEKS C. B., KAFKA R. M. Chronic hypertrophic gastritis. Report of two cases in siblings. Am J Gastroenterol. 1962 May;37:525–536. [PubMed] [Google Scholar]
  2. CHOKAS W. V., CONNOR D. H., INNES R. C. Giant hypertrophy of the gastric mucosa, hypoproteinemia and edema (Menetrier's disease). Am J Med. 1959 Jul;27(1):125–131. doi: 10.1016/0002-9343(59)90066-x. [DOI] [PubMed] [Google Scholar]
  3. CITRIN Y., STERLING K., HALSTED J. A. The mechanism of hypoproteinemia associated with giant hypertrophy of the gastric mucosa. N Engl J Med. 1957 Nov 7;257(19):906–912. doi: 10.1056/NEJM195711072571902. [DOI] [PubMed] [Google Scholar]
  4. Chouraqui J. P., Roy C. C., Brochu P., Gregoire H., Morin C. L., Weber A. M. Ménétrier's disease in children: report of a patient and review of sixteen other cases. Gastroenterology. 1981 May;80(5 Pt 1):1042–1047. [PubMed] [Google Scholar]
  5. Kraut J. R., Powell R., Hruby M. A., Lloyd-Still J. D. Menetrier's disease in childhood: report of two cases and a review of the literature. J Pediatr Surg. 1981 Oct;16(5):707–711. doi: 10.1016/s0022-3468(81)80557-x. [DOI] [PubMed] [Google Scholar]
  6. Lachman R. S., Martin D. J., Vawter G. F. Thick gastric folds in childhood. Am J Roentgenol Radium Ther Nucl Med. 1971 May;112(1):83–92. doi: 10.2214/ajr.112.1.83. [DOI] [PubMed] [Google Scholar]
  7. Lam S. K., Hui W. K., Ho J., Wong K. P., Rotter J. I., Samloff I. M. Pachydermoperiostosis, hypertrophic gastropathy, and peptic ulcer. Gastroenterology. 1983 Apr;84(4):834–839. [PubMed] [Google Scholar]
  8. Lesser P. B., Falchuk K. R., Singer M., Isselbacher K. J. Menetrier's disease. Report of a case with transient and reversible findings. Gastroenterology. 1975 Jun;68(6):1598–1601. [PubMed] [Google Scholar]
  9. Morson B. C., Sobin L. H., Grundmann E., Johansen A., Nagayo T., Serck-Hanssen A. Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol. 1980 Aug;33(8):711–721. doi: 10.1136/jcp.33.8.711. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Scharschmidt B. F. The natural history of hypertrophic gastrophy (Menetrier's disease). Report of a case with 16 year follow-up and review of 120 cases from the literature. Am J Med. 1977 Oct;63(4):644–652. doi: 10.1016/0002-9343(77)90210-8. [DOI] [PubMed] [Google Scholar]
  11. Searcy R. M., Malagelada J. R. Ménétrièr's disease and idiopathic hypertrophic gastropathy. Ann Intern Med. 1984 Apr;100(4):565–570. doi: 10.7326/0003-4819-100-4-565. [DOI] [PubMed] [Google Scholar]
  12. Tan D. T., Stempien S. J., Dagradi A. E. The clinical spectrum of hypertrophic hypersecretory gastropathy. Report of 50 patients. Gastrointest Endosc. 1971 Nov;18(2):69–73. doi: 10.1016/s0016-5107(71)74033-4. [DOI] [PubMed] [Google Scholar]

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