Abstract
An asymptomatic population of 37,000 people in the Nottingham area were offered faecal occult blood tests in a screening study for colorectal cancer. Seventeen thousand nine hundred and thirty people completed the tests and 481 individuals with positive tests underwent full investigation of the colon. Eight people with previously undiagnosed inflammatory bowel disease were identified. In five cases there was total ulcerative colitis; in one a proctitis and in two Crohn's disease. Two further patients with ulcerative colitis were identified; they had been lost to follow up for 25 and 45 years respectively. The combined prevalence of inflammatory bowel disease was 56/10(5) and it is likely that current studies of the epidemiology of these conditions may underestimate the true prevalence by between 27% and 38%.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Binder V., Both H., Hansen P. K., Hendriksen C., Kreiner S., Torp-Pedersen K. Incidence and prevalence of ulcerative colitis and Crohn's disease in the County of Copenhagen, 1962 to 1978. Gastroenterology. 1982 Sep;83(3):563–568. [PubMed] [Google Scholar]
- Devlin H. B., Datta D., Dellipiani A. W. The incidence and prevalence of inflammatory bowel disease in North Tees Health District. World J Surg. 1980;4(2):183–193. doi: 10.1007/BF02393573. [DOI] [PubMed] [Google Scholar]
- Evans J. G., Acheson E. D. An epidemiological study of ulcerative colitis and regional enteritis in the Oxford area. Gut. 1965 Aug;6(4):311–324. doi: 10.1136/gut.6.4.311. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Farrands P. A., Hardcastle J. D. Accuracy of occult blood tests over a six-day period. Clin Oncol. 1983 Sep;9(3):217–225. [PubMed] [Google Scholar]
- Mayberry J. F., Rhodes J. Epidemiological aspects of Crohn's disease: a review of the literature. Gut. 1984 Aug;25(8):886–899. doi: 10.1136/gut.25.8.886. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mayberry J. F., Rhodes J., Newcombe R. G. Familial prevalence of inflammatory bowel disease in relatives of patients with Crohn's disease. Br Med J. 1980 Jan 12;280(6207):84–84. doi: 10.1136/bmj.280.6207.84. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mayberry J. F. Some aspects of the epidemiology of ulcerative colitis. Gut. 1985 Sep;26(9):968–974. doi: 10.1136/gut.26.9.968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mayberry J., Rhodes J., Hughes L. E. Incidence of Crohn's disease in Cardiff between 1934-1977. Gut. 1979 Jul;20(7):602–608. doi: 10.1136/gut.20.7.602. [DOI] [PMC free article] [PubMed] [Google Scholar]