Skip to main content
Gut logoLink to Gut
. 1986 Nov;27(11):1394–1398. doi: 10.1136/gut.27.11.1394

Collagenous colitis associated with small intestinal villous atrophy.

I Hamilton, S Sanders, D Hopwood, I A Bouchier
PMCID: PMC1434063  PMID: 3792923

Abstract

Two patients diagnosed as having small intestinal hyperplastic villous atrophy and being treated with a gluten free diet were investigated because of persistent watery diarrhoea. Both were found to have collagenous colitis. Previous reports of this condition have emphasised the presence of normal small intestinal mucosal architecture and the association of collagenous colitis with intestinal villous atrophy has not previously been reported. Both cases responded to oral steroid therapy, but not to other previously recommended treatment regimens.

Full text

PDF

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bossart R., Henry K., Booth C. C., Doe W. F. Subepithelial collagen in intestinal malabsorption. Gut. 1975 Jan;16(1):18–22. doi: 10.1136/gut.16.1.18. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Colina F., Solis-Herruzo J. A., Munoz-Yagüe M. T., Vazquez G., Perez-Barrios A. Collagenous colitis: the clinical and morphological features. Postgrad Med J. 1982 Jun;58(680):390–395. doi: 10.1136/pgmj.58.680.390. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Debongnie J. C., De Galocsy C., Caholessur M. O., Haot J. Collagenous colitis: a transient condition? Report of two cases. Dis Colon Rectum. 1984 Oct;27(10):672–676. doi: 10.1007/BF02553363. [DOI] [PubMed] [Google Scholar]
  4. Eaves E. R., Wallis P. L., McIntyre R. L., Korman M. G. Collagenous colitis: a recently recognised reversible clinicopathological entity. Aust N Z J Med. 1983 Dec;13(6):630–632. doi: 10.1111/j.1445-5994.1983.tb02619.x. [DOI] [PubMed] [Google Scholar]
  5. Farah D. A., Mills P. R., Lee F. D., McLay A., Russell R. I. Collagenous colitis: possible response to sulfasalazine and local steroid therapy. Gastroenterology. 1985 Mar;88(3):792–797. doi: 10.1016/0016-5085(85)90153-2. [DOI] [PubMed] [Google Scholar]
  6. Fausa O., Foerster A., Hovig T. Collagenous colitis. A clinical, histological, and ultrastructural study. Scand J Gastroenterol Suppl. 1985;107:8–23. doi: 10.3109/00365528509099747. [DOI] [PubMed] [Google Scholar]
  7. Flejou J. F., Grimaud J. A., Molas G., Baviera E., Potet F. Collagenous colitis. Ultrastructural study and collagen immunotyping of four cases. Arch Pathol Lab Med. 1984 Dec;108(12):977–982. [PubMed] [Google Scholar]
  8. Gledhill A., Cole F. M. Significance of basement membrane thickening in the human colon. Gut. 1984 Oct;25(10):1085–1088. doi: 10.1136/gut.25.10.1085. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Guarda L. A., Nelson R. S., Stroehlein J. R., Korinek J. K., Raymond A. K. Collagenous colitis. Am J Clin Pathol. 1983 Oct;80(4):503–507. doi: 10.1093/ajcp/80.4.503. [DOI] [PubMed] [Google Scholar]
  10. Mogensen A. M., Olsen J. H., Gudmand-Høyer E. Collagenous colitis. Acta Med Scand. 1984;216(5):535–540. doi: 10.1111/j.0954-6820.1984.tb05043.x. [DOI] [PubMed] [Google Scholar]
  11. Pieterse A. S., Hecker R., Rowland R. Collagenous colitis: a distinctive and potentially reversible disorder. J Clin Pathol. 1982 Mar;35(3):338–340. doi: 10.1136/jcp.35.3.338. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Rask-Madsen J., Grove O., Hansen M. G., Bukhave K., Scient C., Henrik-Nielsen R. Colonic transport of water and electrolytes in a patient with secretory diarrhea due to collagenous colitis. Dig Dis Sci. 1983 Dec;28(12):1141–1146. doi: 10.1007/BF01295815. [DOI] [PubMed] [Google Scholar]
  13. Teglbjaerg P. S., Thaysen E. H. Collagenous colitis: an ultrastructural study of a case. Gastroenterology. 1982 Mar;82(3):561–563. [PubMed] [Google Scholar]
  14. van den Oord J. J., Geboes K., Desmet V. J. Collagenous colitis: an abnormal collagen table? Two new cases and review of the literature. Am J Gastroenterol. 1982 Jun;77(6):377–381. [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES