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. 1988 Sep;29(9):1173–1179. doi: 10.1136/gut.29.9.1173

Colonic mass movements in idiopathic chronic constipation.

G Bassotti 1, M Gaburri 1, B P Imbimbo 1, L Rossi 1, F Farroni 1, M A Pelli 1, A Morelli 1
PMCID: PMC1434376  PMID: 3197990

Abstract

As relatively little is known of human colonic motor activity either in health, or in pathological conditions, we investigated mass movements in 14 chronically constipated patients and 18 healthy volunteers. Mass movements were recorded from proximal and distal colon during 24 h (12 noon-12 noon) by a colonoscopically positioned multilumen manometric probe and low compliance infusion system. Patients and controls differed significantly in the number (mean 2.6 (0.7) v 6.1 (0.9) (SE), p = 0.02) and duration (mean 8.2 (1.6) v 14.1 (0.8) s, p = 0.04) of mass movements. The data suggest that one pathophysiological mechanism of constipation may be decreased propulsive activity. A circadian pattern, with a significant difference between day and night distribution, was documented in both groups. The patients reported decreased defecatory stimulus concomitant with the mass movements.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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