Abstract
Caerulein, gastrin and pentagastrin stimulation of the Na+/H+ exchange leads to intracellular alkalinisation in pancreatic acinar cells. Activation of protein kinase-C is the more probable mechanism involved in the effect of caerulein.
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Selected References
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- Busa W. B., Nuccitelli R. Metabolic regulation via intracellular pH. Am J Physiol. 1984 Apr;246(4 Pt 2):R409–R438. doi: 10.1152/ajpregu.1984.246.4.R409. [DOI] [PubMed] [Google Scholar]
- Dufresne M., Bastie M. J., Vaysse N., Creach Y., Hollande E., Ribet A. The amiloride sensitive Na+/H+ antiport in guinea pig pancreatic acini. Characterization and stimulation by caerulein. FEBS Lett. 1985 Jul 22;187(1):126–130. doi: 10.1016/0014-5793(85)81227-8. [DOI] [PubMed] [Google Scholar]
- Hellmessen W., Christian A. L., Fasold H., Schulz I. Coupled Na+-H+ exchange in isolated acinar cells from rat exocrine pancreas. Am J Physiol. 1985 Jul;249(1 Pt 1):G125–G136. doi: 10.1152/ajpgi.1985.249.1.G125. [DOI] [PubMed] [Google Scholar]
- L'Allemain G., Paris S., Pouysségur J. Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na+/H+ antiport. J Biol Chem. 1984 May 10;259(9):5809–5815. [PubMed] [Google Scholar]
- Moolenaar W. H. Effects of growth factors on intracellular pH regulation. Annu Rev Physiol. 1986;48:363–376. doi: 10.1146/annurev.ph.48.030186.002051. [DOI] [PubMed] [Google Scholar]
- Schuldiner S., Rozengurt E. Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization. Proc Natl Acad Sci U S A. 1982 Dec;79(24):7778–7782. doi: 10.1073/pnas.79.24.7778. [DOI] [PMC free article] [PubMed] [Google Scholar]
