Abstract
Mailed questionnaires were used to examine the success of PKU (phenylketonuria) screening programs that were operated by departments of health and to examine differences between these programs. Of 55 departments, 44 were returned and 42 departments reported they had a PKU detection program. Thirty-eight respondents considered the PKU detection program to be effective, and 31 respondents indicated that the entire program cost $60,000 or less per year. The answers and comments on the questionnaires showed a generally positive view of the effectiveness about the value of the treatment program in general were also positive. However, a few departments indicated that more clinical evidence and experience were needed to fully evaluate the overall merits of PKU detection and screening programs.
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Selected References
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- ARMSTRONG M. D., LOW N. L. Phenylketonuria VIII. Relation between age, serum phenylalanine level, and phenylpyruvic acid excretion. Proc Soc Exp Biol Med. 1957 Jan;94(1):142–146. doi: 10.3181/00379727-94-22880. [DOI] [PubMed] [Google Scholar]
- Bessman S. P. Legislation and advances in medical knowledge--acceleration or inhibition? J Pediatr. 1966 Aug;69(2):334–338. doi: 10.1016/s0022-3476(66)80350-5. [DOI] [PubMed] [Google Scholar]
- Carpenter G. G., Auerbach V. H., DiGeorge A. M. Phenylalaninemia. Pediatr Clin North Am. 1968 May;15(2):313–323. doi: 10.1016/s0031-3955(16)32124-1. [DOI] [PubMed] [Google Scholar]
- Fuller R., Shuman J. Treated phenylketonuria: intelligence and blood phenylalanine levels. Am J Ment Defic. 1971 Mar;75(5):539–545. [PubMed] [Google Scholar]
- HAAB W., APPLETON M. D., DUCH D., MURRAY R. VALIDATION OF A MODIFICATION OF THE GUTHRIE TEST FOR PHENYLKETONURIA. Am J Ment Defic. 1965 May;69:790–793. [PubMed] [Google Scholar]
- KLEINMAN D. S. PHENYLKETONURIA. A REVIEW OF SOME DEFICITS IN OUR INFORMATION. Pediatrics. 1964 Jan;33:123–134. [PubMed] [Google Scholar]
- KNOX W. E. An evaluation of the treatment of phenylketonuria with diets low in phenylalanine. Pediatrics. 1960 Jul;26:1–11. [PubMed] [Google Scholar]
- Kang E. S., Kaufman S., Gerald P. S. Clinical and biochemical observations of patients with atypical phenylketonuria. Pediatrics. 1970 Jan;45(1):83–92. [PubMed] [Google Scholar]
- UMBARGER B., BERRY H. K., SUTHERLAND B. S. ADVANCES IN THE MANAGEMENT OF PATIENT WITH PHENYLKETONURIA. JAMA. 1965 Sep 6;193:784–790. doi: 10.1001/jama.1965.03090100030007. [DOI] [PubMed] [Google Scholar]