Abstract
The relationship between obesity and 18 different disease conditions was examined in a cross-sectional study of 73,000 weight-conscious women (TOPS Club members). The women reported an average of 1.6 disease conditions each (based on their responses on a questionnaire). Age-specific rates of occurrence for the age group 30-49 years were calculated for each disease condition. The conditions that were found to be significantly (P smaller than 0.001) correlated with obesity were diabetes, high blood pressure, gallbladder disease, gout, thyroid disease, heart disease, arthritis, and jaundice. When the crude relative risks of obesity for each disease condition were calculated, diabetes was found to be the highest (4.5), high blood pressure was second (3.3), and gallbladder disease was third (2.7).
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- ARMSTRONG D. B., DUBLIN L. I., WHEATLEY G. M., MARKS H. H. Obesity and its relation to health and disease. J Am Med Assoc. 1951 Nov 10;147(11):1007–1014. doi: 10.1001/jama.1951.03670280009003. [DOI] [PubMed] [Google Scholar]
- Abraham S., Collins G., Nordsieck M. Relationship of childhood weight status to morbidity in adults. HSMHA Health Rep. 1971 Mar;86(3):273–284. [PMC free article] [PubMed] [Google Scholar]
- BLOOMER H. A., KYLE L. H. Myxedema; a reevaluation of clinical diagnosis based on eighty cases. AMA Arch Intern Med. 1959 Aug;104(2):234–241. doi: 10.1001/archinte.1959.00270080060007. [DOI] [PubMed] [Google Scholar]
- Bernstein R. A., Werner L. H., Rimm A. A. Relationship of gallbladder disease to parity, obesity, and age. Health Serv Rep. 1973 Dec;88(10):925–936. [PMC free article] [PubMed] [Google Scholar]
- Bloom A. Obesity and diabetes; a review. Postgrad Med J. 1971 Jun;47(Suppl):430–434. [PubMed] [Google Scholar]
- Chiang B. N., Perlman L. V., Epstein F. H. Overweight and hypertension. A review. Circulation. 1969 Mar;39(3):403–421. doi: 10.1161/01.cir.39.3.403. [DOI] [PubMed] [Google Scholar]
- Drash A. Obesity and diabetes in childhood. J Fla Med Assoc. 1971 May;58(5):38–40. [PubMed] [Google Scholar]
- Epstein F. H. The epidemiology of coronary heart disease. A review. J Chronic Dis. 1965 Aug;18(8):735–774. doi: 10.1016/0021-9681(65)90017-2. [DOI] [PubMed] [Google Scholar]
- Florey C. du V. The use and interpretation of ponderal index and other weight-height ratios in epidemiological studies. J Chronic Dis. 1970 Aug;23(2):93–103. doi: 10.1016/0021-9681(70)90068-8. [DOI] [PubMed] [Google Scholar]
- Friedman G. D., Kannel W. B., Dawber T. R. The epidemiology of gallbladder disease: observations in the Framingham Study. J Chronic Dis. 1966 Mar;19(3):273–292. doi: 10.1016/0021-9681(66)90132-9. [DOI] [PubMed] [Google Scholar]
- Heyden S., Hames C. G., Bartel A., Cassel J. C., Tyroler H. A., Cornoni J. C. Weight and weight history in relation to cerebrovascular and ischemic heart disease. Arch Intern Med. 1971 Dec;128(6):956–960. [PubMed] [Google Scholar]
- Hinkle L. E., Jr, Whitney L. H., Lehman E. W., Dunn J., Benjamin B., King R., Plakun A., Flehinger B. Occupation, education, and coronary heart disease. Risk is influenced more by education and background than by occupational experiences, in the Bell System. Science. 1968 Jul 19;161(3838):238–246. doi: 10.1126/science.161.3838.238. [DOI] [PubMed] [Google Scholar]
- Ingelfinger F. J. Digestive disease as a national problem. V. Gallstones. Gastroenterology. 1968 Jul;55(1):102–104. [PubMed] [Google Scholar]
- Kalkhoff R., Ferrou C. Metabolic differences between obese overweight and muscular overweight men. N Engl J Med. 1971 Jun 3;284(22):1236–1239. doi: 10.1056/NEJM197106032842203. [DOI] [PubMed] [Google Scholar]
- Mann G. V. Obesity, the nutritional spook. Am J Public Health. 1971 Aug;61(8):1491–1498. doi: 10.2105/ajph.61.8.1491. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reigel D. H., Larson S. J., Sances A., Jr, Hoffman N. E., Switala K. J. A gastric acid inhibitor of cerebral origin. Surgery. 1971 Aug;70(2):161–168. [PubMed] [Google Scholar]
- Sampliner R. E., Bennett P. H., Comess L. J., Rose F. A., Burch T. A. Gallbladder disease in pima indians. Demonstration of high prevalence and early onset by cholecystography. N Engl J Med. 1970 Dec 17;283(25):1358–1364. doi: 10.1056/NEJM197012172832502. [DOI] [PubMed] [Google Scholar]
- Thistle J. L., Eckhart K. L., Jr, Nensel R. E., Nobrega F. T., Poehling G. G., Reimer M., Schoenfield L. J. Prevalence of gallbladder disease among Chippewa Indians. Mayo Clin Proc. 1971 Sep;46(9):603–608. [PubMed] [Google Scholar]