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. 1985 Apr;47(4):567–571. doi: 10.1016/S0006-3495(85)83952-7

Voltage-dependent removal of sodium inactivation by N-bromoacetamide and pronase.

V L Salgado, J Z Yeh, T Narahashi
PMCID: PMC1435119  PMID: 2580570

Abstract

When perfused internally through crayfish giant axons, pronase removed sodium inactivation more than three times as fast at -100 mV as compared with -30 mV. N-bromoacetamide, applied internally, removed sodium inactivation twice as fast at -100 mV as at -30 mV, and the relative rate of removal declined with membrane depolarization in proportion to steady-state sodium inactivation. We conclude that in the closed conformation the sodium inactivation gate is partially protected from destruction by N-bromoacetamide and pronase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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