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. 1980 Oct;73(10):727–730.

Comparison of the effects of atropine and glycopyrrolate on various end-organs1

R K Mirakhur, J W Dundee
PMCID: PMC1438092  PMID: 7241426

Abstract

Atropine and glycopyrrolate (glycopyrronium bromide), a quaternary ammonium drug, were evaluated in volunteers following intramuscular administration with respect to effects on various end-organs with cholinergic innervation. Glycopyrrolate appears to be five to six times more potent than atropine in its antisialogogue effect and also exhibits a selective, though prolonged, effect on salivary secretion and sweat gland activity. It has minimal cardiovascular, ocular and central nervous system effects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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