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. 1981 Mar;74(3):201–204. doi: 10.1177/014107688107400308

Significance of arcus senilis in Caucasians1

Nigel T Cooke
PMCID: PMC1438300  PMID: 7205858

Abstract

A study of arcus senilis in Caucasian men and women is reported. The prevalence of arcus senilis increases with age in both sexes and occurs more frequently in men. In women arcus senilis is uncommon before the menopause. The occurrence of arcus senilis in Caucasians is not a significant finding, except in men under the age of 40 years, when it is associated with an increased risk of coronary artery disease.

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Selected References

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  1. ANDREWS J. S. The lipids of arcus senilis. Arch Ophthalmol. 1962 Aug;68:264–266. doi: 10.1001/archopht.1962.00960030268020. [DOI] [PubMed] [Google Scholar]
  2. BEAUMONT J. L., RICHARD J. L., ANGUERA G., LENEGRE J. [The clinical significance of gerontoxon (arcus corneae)]. 1960 Apr 6-May 29Bull Mem Soc Med Hop Paris. 76:637–646. [PubMed] [Google Scholar]
  3. COGAN D. G., KUWABARA T. Arcus senilis; its pathology and histochemistry. AMA Arch Ophthalmol. 1959 Apr;61(4):553–560. [PubMed] [Google Scholar]
  4. Hickey N., Maurer B., Mulcahy R. Arcus senilis: its relation to certain attributes and risk factors in patients with coronary heart disease. Br Heart J. 1970 Jul;32(4):449–452. doi: 10.1136/hrt.32.4.449. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Klein B., Klein R., Haseman J., Maready J., Hames C. Corneal arcus and cardiovascular disease in Evans County, Georgia. Arch Intern Med. 1975 Apr;135(4):509–511. [PubMed] [Google Scholar]
  6. LINDHOLM H. Arcus lipoides corneae and arteriosclerosis. Acta Med Scand. 1960 Sep 21;168:45–49. doi: 10.1111/j.0954-6820.1960.tb06640.x. [DOI] [PubMed] [Google Scholar]
  7. MCANDREW G. M., OGSTON D. ARCUS SENILIS IN MIDDLE-AGED MEN. Br Med J. 1965 Feb 13;1(5432):425–427. doi: 10.1136/bmj.1.5432.425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Macaraeg P. V., Jr, Lasagna L., Snyderb Arcus not so senilis. Ann Intern Med. 1968 Feb;68(2):345–354. doi: 10.7326/0003-4819-68-2-345. [DOI] [PubMed] [Google Scholar]
  9. McAndrew G. M., Ogston D. Arcus senilis and coronary artery disease. Am Heart J. 1965 Dec;70(6):838–840. doi: 10.1016/0002-8703(65)90343-1. [DOI] [PubMed] [Google Scholar]
  10. OLIVER M. F., BOYD G. S. Effect of bilateral ovariectomy on coronary-artery disease and serum-lipid levels. Lancet. 1959 Oct 31;2(7105):690–694. doi: 10.1016/s0140-6736(59)92129-4. [DOI] [PubMed] [Google Scholar]
  11. RIFKIND B. M. THE INCIDENCE OF ARCUS SENILIS IN ISCHAEMIC HEART-DISEASE ITS RELATION TO SERUM-LIPID LEVELS. Lancet. 1965 Feb 6;1(7380):312–314. doi: 10.1016/s0140-6736(65)91044-5. [DOI] [PubMed] [Google Scholar]
  12. RODSTEIN M., ZEMAN F. D. Arcus senilis and arteriosclerosis in the aged. Am J Med Sci. 1963 Jan;245:70–77. [PubMed] [Google Scholar]
  13. Rosenman R. H., Brand R. J., Sholtz R. I., Jenkins C. D. Relation of corneal arcus to cardiovascular risk factors and the incidence of coronary disease. N Engl J Med. 1974 Dec 19;291(25):1322–1324. doi: 10.1056/NEJM197412192912503. [DOI] [PubMed] [Google Scholar]
  14. SHANOFF H. M., LITTLE J. A. STUDIES OF MALE SURVIVORS OF MYOCARDIAL INFARCTION DUE TO "ESSENTIAL" ATHEROSCLEROSIS. 3. CORNEAL ARCUS: INCIDENCE AND RELATION TO SERUM LIPIDS AND LIPOPROTEINS. Can Med Assoc J. 1964 Oct 17;91:835–839. [PMC free article] [PubMed] [Google Scholar]
  15. Schatz I. J. Classification of primary hyperlipidemia. Observations on 214 patients. JAMA. 1969 Oct 27;210(4):701–704. [PubMed] [Google Scholar]
  16. Thomas J. V., Ewing J. A., Desrosiers N. A. Alcohol consumption and arcus senilis: a search for a significant relationship. Br J Addict Alcohol Other Drugs. 1972 Sep;67(3):177–179. doi: 10.1111/j.1360-0443.1972.tb01190.x. [DOI] [PubMed] [Google Scholar]

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