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. 1983 May;76(5):354–358. doi: 10.1177/014107688307600505

Effects of anterior temporal lobectomy apart from the relief of seizures: a study of 40 patients1

C E Polkey
PMCID: PMC1439178  PMID: 6864700

Abstract

The effect of temporal lobectomy, apart from the relief of seizures, is described in 40 patients undergoing the operation and followed up for between 2 and 6 years. Changes in their intellectual performance and mental state are described, and the possible mechanisms of these changes are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Babb T. L., Crandall P. H. Epileptogenesis of human limbic neurons in psychomotor epileptics. Electroencephalogr Clin Neurophysiol. 1976 Mar;40(3):225–243. doi: 10.1016/0013-4694(76)90147-4. [DOI] [PubMed] [Google Scholar]
  2. Bear D. M., Fedio P. Quantitative analysis of interictal behavior in temporal lobe epilepsy. Arch Neurol. 1977 Aug;34(8):454–467. doi: 10.1001/archneur.1977.00500200014003. [DOI] [PubMed] [Google Scholar]
  3. Bear D. M. Temporal lobe epilepsy--a syndrome of sensory-limbic hyperconnection. Cortex. 1979 Sep;15(3):357–384. doi: 10.1016/s0010-9452(79)80064-7. [DOI] [PubMed] [Google Scholar]
  4. Blakemore C. B., Falconer M. A. Long-term effects of anterior temporal lobectomy on certain cognitive functions. J Neurol Neurosurg Psychiatry. 1967 Aug;30(4):364–367. doi: 10.1136/jnnp.30.4.364. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Crandall P. H. Neurosurgical management of the epilepsies. Postoperative management and criteria for evaluation. Adv Neurol. 1975;8:265–279. [PubMed] [Google Scholar]
  6. Currie S., Heathfield K. W., Henson R. A., Scott D. F. Clinical course and prognosis of temporal lobe epilepsy. A survey of 666 patients. Brain. 1971;94(1):173–190. doi: 10.1093/brain/94.1.173. [DOI] [PubMed] [Google Scholar]
  7. Falconer M. A., Taylor D. C. Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis. Etiology and significance. Arch Neurol. 1968 Oct;19(4):353–361. doi: 10.1001/archneur.1968.00480040019001. [DOI] [PubMed] [Google Scholar]
  8. Flor-Henry P. Psychosis and temporal lobe epilepsy. A controlled investigation. Epilepsia. 1969 Sep;10(3):363–395. doi: 10.1111/j.1528-1157.1969.tb03853.x. [DOI] [PubMed] [Google Scholar]
  9. Halgren E., Walter R. D., Cherlow D. G., Crandall P. H. Mental phenomena evoked by electrical stimulation of the human hippocampal formation and amygdala. Brain. 1978 Mar;101(1):83–117. doi: 10.1093/brain/101.1.83. [DOI] [PubMed] [Google Scholar]
  10. Jensen I., Klinken L. Temporal lobe epilepsy and neuropathology. Histological findings in resected temporal lobes correlated to surgical results and clinical aspects. Acta Neurol Scand. 1976 Nov;54(5):391–414. doi: 10.1111/j.1600-0404.1976.tb04372.x. [DOI] [PubMed] [Google Scholar]
  11. Jensen I., Larsen J. K. Psychoses in drug-resistant temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 1979 Oct;42(10):948–954. doi: 10.1136/jnnp.42.10.948. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Polkey C. E. Selection of patients with chronic drug-resistant epilepsy for resective surgery: 5 years' experience. J R Soc Med. 1981 Aug;74(8):574–579. doi: 10.1177/014107688107400804. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Rasmussen T. Surgical aspects of temporal lobe epilepsy. Results and problems. Acta Neurochir Suppl (Wien) 1980;30:13–24. doi: 10.1007/978-3-7091-8592-6_3. [DOI] [PubMed] [Google Scholar]
  14. SERAFETINIDES E. A., FALCONER M. A. The effects of temporal lobectomy in epileptic patients with psychosis. J Ment Sci. 1962 Sep;108:584–593. doi: 10.1192/bjp.108.456.584. [DOI] [PubMed] [Google Scholar]
  15. Sherwin I. Psychosis associated with epilepsy: significance of the laterality of the epileptogenic lesion. J Neurol Neurosurg Psychiatry. 1981 Jan;44(1):83–85. doi: 10.1136/jnnp.44.1.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Taylor D. C. Factors influencing the occurrence of schizophrenia-like psychosis in patients with temporal lobe epilepsy. Psychol Med. 1975 Aug;5(3):249–254. doi: 10.1017/s0033291700056609. [DOI] [PubMed] [Google Scholar]
  17. Taylor D. C., Falconer M. A. Clinical, socio-economic, and psychological changes after temporal lobectomy for epilepsy. Br J Psychiatry. 1968 Oct;114(515):1247–1261. doi: 10.1192/bjp.114.515.1247. [DOI] [PubMed] [Google Scholar]

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