Abstract
Mycosis fungoides (MF) is an uncommon T-cell lymphoma which characteristically involves the skin. Two patients with MF are described who developed fatal complications secondary to involvement of the gastrointestinal tract. One developed malabsorption due to small intestinal involvement; the other had a massive haemorrhage from an ulcerated nodule of tumour in the stomach. The potential for extracutaneous spread is discussed, and it is emphasized that bowel infiltration should be considered in any patient with MF who develops gastrointestinal symptoms or complications.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chu A. C., Morgan E. W., MacDonald D. M. Evaluation of acid alpha-naphthyl acetate esterase activity as a marker of T lymphocytes in benign and neoplastic cutaneous infiltrates. Br J Dermatol. 1981 Jan;104(1):31–36. doi: 10.1111/j.1365-2133.1981.tb01708.x. [DOI] [PubMed] [Google Scholar]
- Epstein E. H., Jr, Levin D. L., Croft J. D., Jr, Lutzner M. A. Mycosis fungoides. Survival, prognostic features, response to therapy, and autopsy findings. Medicine (Baltimore) 1972 Jan;51(1):61–72. [PubMed] [Google Scholar]
- Gazdar A. F., Carney D. N., Russell E. K., Schechter G. P., Bunn P. A., Jr In vitro growth of cutaneous T-cell lymphomas. Cancer Treat Rep. 1979 Apr;63(4):587–590. [PubMed] [Google Scholar]
- Rappaport H., Thomas L. B. Mycosis fungoides: the pathology of extracutaneous involvement. Cancer. 1974 Oct;34(4):1198–1229. doi: 10.1002/1097-0142(197410)34:4<1198::aid-cncr2820340431>3.0.co;2-e. [DOI] [PubMed] [Google Scholar]
- Wolfe J. D., Trevor E. D., Kjeldsberg C. R. Pulmonary manifestations of mycosis fungoides. Cancer. 1980 Dec 15;46(12):2648–2653. doi: 10.1002/1097-0142(19801215)46:12<2648::aid-cncr2820461219>3.0.co;2-1. [DOI] [PubMed] [Google Scholar]
- Zackheim H. S. Cutaneous T-cell lymphomas. A review of the recent literature. Arch Dermatol. 1981 May;117(5):295–304. doi: 10.1001/archderm.117.5.295. [DOI] [PubMed] [Google Scholar]