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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1984 Dec 15;131(12):1469–1470.

Hemolytic anemia following insertion of Ionescu-Shiley mitral valve bioprosthesis.

S B Reddy, J L Pater, J Pym, P W Armstrong
PMCID: PMC1440344  PMID: 6498703

Abstract

Hemolytic anemia is a relatively common complication after the replacement of cardiac valves with mechanical prostheses; the prevalence rate varies from 38% to 85%, depending on the prosthesis implanted. However, cardiac valves fabricated from biologic material are associated with a reduced incidence of hemolytic anemia, and to the authors' knowledge this report is the first to document hemolytic anemia in a patient who had the mitral valve replaced with an Ionescu-Shiley valve. The anemia was not associated with evidence of hemodynamically important mitral regurgitation and was ultimately controlled by iron and folate supplements.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ahmad R., Manohitharajah S. M., Deverall P. B., Watson D. A. Chronic hemolysis following mitral valve replacement. A comparative study of the Björk-Shiley, composite-seat Starr-Edwards, and frame-mounted aortic homograft valves. J Thorac Cardiovasc Surg. 1976 Feb;71(2):212–217. [PubMed] [Google Scholar]
  2. Crexells C., Aerichide N., Bonny Y., Lepage G., Campeau L. Factors influencing hemolysis in valve prosthesis. Am Heart J. 1972 Aug;84(2):161–170. doi: 10.1016/0002-8703(72)90330-4. [DOI] [PubMed] [Google Scholar]
  3. Dave K. S., Madan C. K., Pakrashi B. C., Roberts B. E., Ionescu M. I. Chronic hemolysis following fascia lata and Starr-Edwards aortic valve replacement. Circulation. 1972 Aug;46(2):240–249. doi: 10.1161/01.cir.46.2.240. [DOI] [PubMed] [Google Scholar]
  4. Febres-Roman P. R., Bourg W. C., Crone R. A., Davis R. C., Jr, Williams T. H. Chronic intravascular hemolysis after aortic valve replacement with Ionescu-Shiley xenograft: comparative study with Bjork-Shiley prosthesis. Am J Cardiol. 1980 Nov;46(5):735–738. doi: 10.1016/0002-9149(80)90422-1. [DOI] [PubMed] [Google Scholar]
  5. Febres-Roman P. R., Haas J. M., Cowen G. D. Hemodynamic assessment of the Ionescu-Shiley pericardial xenograft in the mitral position. Cathet Cardiovasc Diagn. 1980;6(3):233–245. doi: 10.1002/ccd.1810060304. [DOI] [PubMed] [Google Scholar]
  6. Goldberger A. L., Orth R., Moores W. Y. Severe hemolytic anemia after attempted repair of paraprosthetic mitral regurgitation. Am Heart J. 1982 Dec;104(6):1381–1382. doi: 10.1016/0002-8703(82)90175-2. [DOI] [PubMed] [Google Scholar]
  7. Ionescu M. I., Pakrashi B. C., Mary D. A., Bartek I. T., Wooler G. H., McGoon D. C. Long-term evaluation of tissue valves. J Thorac Cardiovasc Surg. 1974 Sep;68(3):361–379. [PubMed] [Google Scholar]
  8. Magilligan D. J., Jr, Fisher E., Alam M. Hemolytic anemia with porcine xenograft aortic and mitral valves. J Thorac Cardiovasc Surg. 1980 Apr;79(4):628–631. [PubMed] [Google Scholar]
  9. Myers T. J., Hild D. H., Rinaldi M. J. Hemolytic anemia associated with heterograft replacement of the mitral valve. J Thorac Cardiovasc Surg. 1978 Aug;76(2):214–215. [PubMed] [Google Scholar]
  10. Rao K. R., Patel A. R., Patel R. N., Kumaraiah V., Towne W. D. Erythrocyte survival in patients with porcine xenograft aortic and mitral valves. South Med J. 1982 Mar;75(3):296–297. doi: 10.1097/00007611-198203000-00013. [DOI] [PubMed] [Google Scholar]
  11. Rhodes G. R., McIntosh C. L. Evaluation of hemolysis following replacement of atrioventricular valves with procine xenograft (Hancock) valves. J Thorac Cardiovasc Surg. 1977 Feb;73(2):312–315. [PubMed] [Google Scholar]
  12. Roeser W. H., Powell L. W., O'Brien M. F. Hemolysis after heterograft and prosthetic valve replacement. Am Heart J. 1970 Feb;79(2):281–283. doi: 10.1016/0002-8703(70)90321-2. [DOI] [PubMed] [Google Scholar]

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