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. 1984 Jul 21;289(6438):151–152. doi: 10.1136/bmj.289.6438.151

Anti-Jo-1 antibody: a marker for myositis with interstitial lung disease.

R M Bernstein, S H Morgan, J Chapman, C C Bunn, M B Mathews, M Turner-Warwick, G R Hughes
PMCID: PMC1442006  PMID: 6430389

Abstract

An autoantibody known as anti-Jo-1 antibody is found in 25% of patients with myositis. Its prevalence in patients with both myositis and cryptogenic fibrosing alveolitis was 68% (13 out of 19 patients), compared with 7.5% in patients with myositis alone (four of 53) and 3% in patients with cryptogenic fibrosing alveolitis alone (two of 62). Anti-Jo-1 antibody may be useful in indicating patients with myositis and cryptogenic fibrosing alveolitis. Raynaud's phenomenon, the sicca syndrome, and mild arthritis are also often part of the syndrome.

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Selected References

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